Hermann Josef Gröne

TL;DR: In the presence of bilateral renal artery stenosis and sodium deprivation, systemic blood pressure normalization after the blockade of the RAS may be accompanied by acute renal failure, which may be explained partially by poststenotic renal hypotension, but it may also reflect a reduction of the GFR because of the blockade

TL;DR: It is described, by focused ion beam scanning electron microscopy, that STIL−/− mouse embryos do not contain centrioles or primary cilia, suggesting that these organelles are not essential for mammalian development until mid gestation, and it is shown that the lack ofPrimary cilia explains the absence of Hedgehog signaling in STIL+/− cells.

TL;DR: A novel hydrophilic interaction chromatography-based LC-MS2 method is established and shown to separate corresponding hexosylsphingosine standards, promoting its applicability in further investigations.

TL;DR: O restored renovascular endothelial function and prevented vascular hypertrophy in salt-induced hypertension and therefore may advance as a beneficial approach in the therapy of various forms of hypertension.

TL;DR: Since the decision to offer immunosuppressive therapy in this cohort was intimately associated with the MEST-C score, this study indicates a need for more detailed guidance for pathologists in the scoring of IgAN biopsies.