H
Hermann Josef Gröne
Researcher at German Cancer Research Center
Publications - 357
Citations - 25145
Hermann Josef Gröne is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Kidney & Chemokine. The author has an hindex of 82, co-authored 346 publications receiving 23147 citations.
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Journal ArticleDOI
Absolute quantification of donor-derived cell-free DNA as a marker of rejection and graft injury in kidney transplantation: Results from a prospective observational study.
Michael Oellerich,Maria Shipkova,Thomas Asendorf,Philip D. Walson,Verena Schauerte,Nina Mettenmeyer,Mariana Kabakchiev,Georg Hasche,Hermann Josef Gröne,Tim Friede,Eberhard Wieland,Vedat Schwenger,Ekkehard Schütz,Julia Beck +13 more
TL;DR: Results for acute tubular necrosis (ATN) were not significantly different from those with biopsy‐proven rejection (BPR) and dd‐cfDNA identified unnecessary biopsies triggered by a rise in plasma creatinine, suggesting that dd‐ cfDNA may detect inadequate immunosuppression resulting in subclinical graft damage.
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Effects of Increased Renal Tubular Vascular Endothelial Growth Factor (VEGF) on Fibrosis, Cyst Formation, and Glomerular Disease
Samy Hakroush,Marcus J. Moeller,Franziska Theilig,Brigitte Kaissling,Tjeerd P. Sijmonsma,Manfred Jugold,Ann L. Akeson,Milena Traykova-Brauch,Hiltraud Hosser,Brunhilde Hähnel,Hermann Josef Gröne,Robert Koesters,Wilhelm Kriz +12 more
TL;DR: This study shows that systemic VEGF interferes with the intraglomerular cross-talk between podocytes and the endocapillary compartment, leading to severe deterioration in glomerular architecture, similar to that seen in diabetic nephropathy.
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Male Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis: A LINK TO CERAMIDE SYNTHASE-3*
Mariona Rabionet,Aarnoud C. van der Spoel,Chia Chen Chuang,Benita Von Tümpling-Radosta,Manja Litjens,Diane Bouwmeester,Christina C. Hellbusch,Christian Körner,Herbert Wiegandt,Karin Gorgas,Frances M. Platt,Hermann Josef Gröne,Roger Sandhoff +12 more
TL;DR: The data imply that both glycans and the particular acyl chains of germinal sphingolipids are relevant for proper completion of meiosis, and the latter lipids are not sufficient for completion of spermatogenesis.
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Prediction of Acute Renal Allograft Rejection by Urinary Monokine Induced by IFN-γ (MIG)
Ingeborg A. Hauser,Sandra Spiegler,Eva Kiss,Stefan Gauer,Olaf Sichler,Ernst H. Scheuermann,Hanns Ackermann,Josef Pfeilschifter,Helmut Geiger,Hermann Josef Gröne,Heinfried H. Radeke +10 more
TL;DR: The role of the chemokine monokine induced by MIG and IFN-γ–inducible protein 10 (IP-10) (CXCL10) as early markers of AR in renal transplantation (NTX) is defined.
Journal ArticleDOI
Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis.
Sebastian Bickelhaupt,Christian Erbel,Carmen Timke,Ute Wirkner,Monika Dadrich,Paul Flechsig,Alexandra Tietz,Johanna Pföhler,Wolfgang Gross,Peter Peschke,Line Hoeltgen,Hugo A. Katus,Hermann Josef Gröne,Nils H. Nicolay,Rainer Saffrich,Jürgen Debus,Mark D. Sternlicht,Todd W. Seeley,Kenneth E. Lipson,Peter E. Huber +19 more
TL;DR: It is indicated that blocking CTGF attenuates radiation-induced pulmonary remodeling and can reverse the process after initiation, and FG-3019 may benefit patients with radiation- induced pulmonary fibrosis or patients with other forms or origin of chronic fibrotic diseases.