H
Hermann Josef Gröne
Researcher at German Cancer Research Center
Publications - 357
Citations - 25145
Hermann Josef Gröne is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Kidney & Chemokine. The author has an hindex of 82, co-authored 346 publications receiving 23147 citations.
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Journal ArticleDOI
Loss of matrix metalloproteinase-13 attenuates murine radiation-induced pulmonary fibrosis.
Paul Flechsig,Bettina Hartenstein,Sybille Teurich,Monika Dadrich,Kai Hauser,Amir Abdollahi,Hermann Josef Gröne,Peter Angel,Peter E. Huber +8 more
TL;DR: It is found that MMP13 deficient mice developed less pulmonary fibrosis than their wildtype counterparts, showed attenuated acute pulmonary inflammation (days after irradiation), and a reduction of inflammation during the later fibrogenic phase (5-6 months after irradation).
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Met-RANTES reduces endothelial progenitor cell homing to activated (glomerular) endothelium in vitro and in vivo
Maarten B. Rookmaaker,Marianne C. Verhaar,Hetty C. de Boer,Roel Goldschmeding,Jaap A. Joles,Hein A. Koomans,Hermann Josef Gröne,Ton J. Rabelink +7 more
TL;DR: It is hypothesized that RANTES does not only promote the influx and activation of inflammatory leukocytes but also mediates glomerular microvascular repair by stimulating the homing of bone marrow (BM)-derived endothelial progenitor cells.
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Cell Biological and Biochemical Characterization of Drebrin Complexes in Mesangial Cells and Podocytes of Renal Glomeruli
Wiebke K. Peitsch,Ilse Hofmann,Nicole Endlich,Silke Prätzel,Cäcilia Kuhn,Herbert Spring,Hermann Josef Gröne,Wilhelm Kriz,Werner W. Franke +8 more
TL;DR: The findings confirm and extend the hypothesis that drebrin is involved in the regulation of actin dynamics also outside the nervous system and the dynamics of mesangial cells and foot processes in podocytes.
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The renal microenvironment modifies dendritic cell phenotype
Federica Chessa,Daniel Mathow,Shijun Wang,Thomas Hielscher,Ann Atzberger,Stefan Porubsky,Norbert Gretz,Sven Burgdorf,Hermann Josef Gröne,Zoran V. Popovic +9 more
TL;DR: The medullary environment inhibits an alloimmune response by modulating the phenotype and function of dendritic cells by inhibiting the interstitial osmotic gradient andGene expression profiles of both medullaries and bone marrow-derived d endritic cells matured in hyperosmolar medium had an overlap with the macrophage M2 signature.
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Up-Regulation of the Human Serum and Glucocorticoid-Dependent Kinase 1 in Glomerulonephritis
Bjoern Friedrich,S. Wärntges,Karin Klingel,Martina Sauter,Reinhard Kandolf,Teut Risler,Gerhard A. Müller,Ralph Witzgall,Wilhelm Kriz,Hermann Josef Gröne,Florian Lang +10 more
TL;DR: In conclusion, glomerulonephritis leads to glomerular and in some cases to epithelial up-regulation of hSGK1 transcription, a serine/threonine kinase participating in the regulation of Na+ transport.