Hermann Josef Gröne

TL;DR: This work has developed a technique that can be applied in vivo in intact cells and animals and is based on affinity-chromatographic isolation of thiolated mRNA, which provides a detailed analysis of regulatory mechanisms of mRNA expression and the relative contributions of RNA synthesis and turnover within distinct pathways.

TL;DR: The improvement of glomerular function and amelioration of renal vasculitis and proteinuria with vitamin E cotreatment indicate that oxidants are involved in the pathogenesis of renal injury in this model, but markedly impaired endothelial function and unabated hypertension persist with vitaminE treatment and seem to be directly attributable to NO deficiency.

TL;DR: The results indicate that villin may be a grading marker that deserves further study in renal carcinoma and raise the question whether the majority of renal carcinomas are derived from the proximal tubular epithelium rather than from the distal epithelia.

TL;DR: The data suggest that lipoproteins may play a critical role in mediating mesangial cell hypertrophy or proliferation, events intimately involved in the development of glomerulosclerosis.

TL;DR: In this article, a high-risk cytogenetic group 3 and molecular group C ependymoma model (DKFZ-EP1NS) was generated from a patient with metastatic disease.