H
Hermann Josef Gröne
Researcher at German Cancer Research Center
Publications - 357
Citations - 25145
Hermann Josef Gröne is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Kidney & Chemokine. The author has an hindex of 82, co-authored 346 publications receiving 23147 citations.
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Journal ArticleDOI
A cut-off based approach for gene expression analysis of formalin-fixed and paraffin-embedded tissue samples
Prashant K. Srivastava,Stefan Küffer,Benedikt Brors,Priyanka Shahi,Li Li,Marc Kenzelmann,Norbert Gretz,Hermann Josef Gröne +7 more
TL;DR: The best representation of PC gene expression, as well as better comparability to meta-analysis and fresh-frozen microarray data, could be obtained with a 600-nucleotide cutoff.
Journal ArticleDOI
Angiogenesis and vascular endothelial growth factor (VEGF): is it relevant in renal patients?
Journal ArticleDOI
Molecular and biochemical alterations in tubular epithelial cells of patients with isolated methylmalonic aciduria
Thorsten Ruppert,A. Schumann,Hermann Josef Gröne,Jürgen G. Okun,Stefan Kölker,M. A. Morath,Sven W. Sauer +6 more
TL;DR: In this article, the authors established an in vitro model of tubular epithelial cells from patient urine (hTEC; 9 controls, 5 mut(0), 1 cblB) and found specific tubular markers (AQP1, UMOD, AQP2).
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The Atypical Chemokine Receptor 2 Limits Progressive Fibrosis after Acute Ischemic Kidney Injury.
Moritz Lux,Alexander Blaut,Nuru Eltrich,Andrei Bideak,Martin B. Müller,John M. Hoppe,Hermann Josef Gröne,Massimo Locati,Massimo Locati,Volker Vielhauer +9 more
TL;DR: ACKR2 is important in limiting persistent inflammation, tubular loss, and renal fibrosis after ischemic acute kidney injury and, thus, can prevent progression to chronic renal disease.
Journal ArticleDOI
Inflammation leads through PGE/EP3 signaling to HDAC5/MEF2‐dependent transcription in cardiac myocytes
András Tóth,András Tóth,Richard Schell,Magdolna Levay,Christiane Vettel,Philipp Theis,Clemens Haslinger,Felix Alban,Stefanie Maria Werhahn,Lina Frischbier,Jutta Krebs-Haupenthal,Dominique Thomas,Hermann Josef Gröne,Metin Avkiran,Hugo A. Katus,Thomas Wieland,Johannes Backs +16 more
TL;DR: These findings provide an unexpected new link between inflammation and cardiac remodeling by de‐repression of MEF2 through HDAC5 inactivation, which has potential implications for new strategies to treat inflammatory cardiomyopathies.