Hermann Josef Gröne

TL;DR: In wild‐type mice, Stx2 caused acute tubular dysfunction with consequent electrolyte disturbance, which was most likely the cause of death, and based on these data, one may surmise that acutetubular damage represents a separate pathophysiological mechanism, importantly contributing to Stx1‐mediated acute kidney failure.

TL;DR: This work uncovers semaphorin-plexin signaling as a central regulatory mechanism of mitotic spindle orientation necessary for the alignment of epithelial cell divisions with the epithelial plane.

TL;DR: The genome organization of the novel human papillomavirus type 108 (HPV108), isolated from a low-grade cervical lesion, deviates from those of other HPVs in lacking an E6 gene, and modifications are suggestive of infection by a high-risk papillamavirus.

TL;DR: This work provides the first evidence that only UVB and Mastomys natalensis papillomavirus (MnPV) infection strongly promote NMSC formation, and provides a reasonable explanation for making continuous viral presence dispensable during skin carcinogenesis as observed in patients with N MSC.

TL;DR: The results suggest that CXCL16 and ADAM10 are involved in the recruitment of T cells to the kidney and play an important role in inflammatory kidney diseases.