H
Hermann Josef Gröne
Researcher at German Cancer Research Center
Publications - 357
Citations - 25145
Hermann Josef Gröne is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Kidney & Chemokine. The author has an hindex of 82, co-authored 346 publications receiving 23147 citations.
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Journal ArticleDOI
Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma
Susanne Kleber,Ignacio Sancho-Martinez,B Wiestler,Alexandra Beisel,Christian Gieffers,Oliver Hill,Meinolf Thiemann,Wolf Mueller,Jaromir Sykora,Andreas Kuhn,Nina Schreglmann,Elisabeth Letellier,Cecilia Zuliani,Stefan Klussmann,Marcin Teodorczyk,Hermann Josef Gröne,Tom M. Ganten,Holger Sültmann,Jochen Tüttenberg,Andreas von Deimling,Anne Régnier-Vigouroux,Christel Herold-Mende,Ana Martin-Villalba +22 more
TL;DR: CD95 is uncovered as an activator of PI3K and, most importantly, as a crucial trigger of basal invasion of glioblastoma in vivo.
Journal ArticleDOI
Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line.
Rainer Constien,Anne Forde,Birgit Liliensiek,Hermann Josef Gröne,Peter P. Nawroth,Günter J. Hämmerling,Bernd Arnold +6 more
TL;DR: The successful establishment of a novel knock‐in EGFP reporter mouse line to monitor Cre‐induced recombination in the vast majority of cell types and high efficiency of recombination was found in all endothelial cells and in the majority of hematopoietic cells but was absent in other tissues.
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Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: A gene expression analysis on total and microdissected prostate tissue
Thomas Ernst,Manfred Hergenhahn,Marc Kenzelmann,Clemens D. Cohen,Mahnaz Bonrouhi,Annette Weninger,Ralf Klären,Elisabeth F. Gröne,Manfred Wiesel,Christof Güdemann,Jens Küster,Winfried Schott,Gerd Staehler,Matthias Kretzler,Monica Hollstein,Hermann Josef Gröne +15 more
TL;DR: In this article, DNA microarray data for eight genes were confirmed quantitatively in five normal and five cancer tissues by real-time reverse transcriptase-polymerase chain reaction with a high correlation between the two methods.
Journal ArticleDOI
Tubular Overexpression of Transforming Growth Factor-β1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells
Robert Koesters,Brigitte Kaissling,Michel LeHir,Nicolas Picard,Franziska Theilig,Rolf Gebhardt,Adam B. Glick,Brunhilde Hähnel,Hiltraud Hosser,Hermann Josef Gröne,Wilhelm Kriz +10 more
TL;DR: In conclusion, overexpression of TGF-beta1 in renal tubules in vivo induces interstitial proliferation, tubular autophagy, and fibrosis, but not epithelial-to-mesenchymal transition.
Journal ArticleDOI
Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: blocking monocyte arrest and recruitment
Hermann Josef Gröne,Christian Weber,Kim S. C. Weber,Elisabeth F. Gröne,Ton J. Rabelink,Christiane Klier,Timothy N. C. Wells,Amanda E. I. Proudfoot,Detlef Schlöndorff,Peter J. Nelson +9 more
TL;DR: Met‐RANTES reduces vascular and tubular damage during acute renal transplant rejection: blocking monocyte arrest and recruitment and may counter acute rejection by blocking leukocyte firm adhesion to inflamed endothelium.