H
Hiroshi Tanaka
Researcher at Sapporo Medical University
Publications - 98
Citations - 2599
Hiroshi Tanaka is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Asthma & Mycoplasma pneumoniae. The author has an hindex of 25, co-authored 98 publications receiving 2458 citations.
Papers
More filters
Journal ArticleDOI
Integral role of Noxa in p53-mediated apoptotic response
Tsukasa Shibue,Kiyoshi Takeda,Eri Oda,Hiroshi Tanaka,Hideki Murasawa,Akinori Takaoka,Yasuyuki Morishita,Shizuo Akira,Tadatsugu Taniguchi,Nobuyuki Tanaka +9 more
TL;DR: Noxa(-/-) mice showed resistance to X-ray irradiation-induced gastrointestinal death, accompanied with impaired apoptosis of the epithelial cells of small intestinal crypts, indicating the contribution of Noxa to the p53 response in vivo.
Journal ArticleDOI
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
Tomomitsu Hirota,Atsushi Takahashi,Michiaki Kubo,Tatsuhiko Tsunoda,Kaori Tomita,Satoru Doi,Kimie Fujita,Akihiko Miyatake,Tadao Enomoto,Takehiko Miyagawa,Mitsuru Adachi,Hiroshi Tanaka,Akio Niimi,Hisako Matsumoto,Isao Ito,Hironori Masuko,Tohru Sakamoto,Nobuyuki Hizawa,Masami Taniguchi,John J. Lima,Charles G. Irvin,Stephen P. Peters,Blanca E. Himes,Augusto A. Litonjua,Kelan G. Tantisira,Scott T. Weiss,Naoyuki Kamatani,Yusuke Nakamura,Mayumi Tamari +28 more
TL;DR: The most significant association with adult asthma is observed at rs404860 in the major histocompatiblity complex region, which is close to rs2070600, a SNP previously reported for association with FEV1/FVC in genome-wide association studies for lung function.
Journal ArticleDOI
Quantitative Analysis of Bronchial Wall Vascularity in the Medium and Small Airways of Patients With Asthma and COPD
TL;DR: The number of vessels in the medium and small airways in asthma patients shows a greater increase than those in COPD patients, and the vascular area in the small airway is increased in COPd patients but not in asthma Patients.
Journal ArticleDOI
IL-18 might reflect disease activity in mild and moderate asthma exacerbation.
Hiroshi Tanaka,Naomitsu Miyazaki,Kensuke Oashi,Shin Teramoto,Masanori Shiratori,Midori Hashimoto,Mitsuhide Ohmichi,Shosaku Abe +7 more
TL;DR: It was suggested that IL-18 may play a potential role to activate immunologic responses and may reflect disease activity in mild and moderate asthma exacerbation.
Journal ArticleDOI
Controlled, prospective trial of steroid treatment in IgA nephropathy: a limitation of low-dose prednisolone therapy.
Ritsuko Katafuchi,Kiyoshi Ikeda,Tohru Mizumasa,Hiroshi Tanaka,Takashi Ando,Tetsuro Yanase,Kohsuke Masutani,Michiaki Kubo,Satoru Fujimi +8 more
TL;DR: Data suggest that the protocol had an antiproteinuric effect, but could not improve kidney survival, and an insufficient dose of prednisolone in the protocol may be the reason for the discrepancy between the effect on proteinuria and kidney survival.