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Hong Zhang

Researcher at Chinese Academy of Sciences

Publications -  482
Citations -  15856

Hong Zhang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Synthetic aperture radar & Autophagy. The author has an hindex of 52, co-authored 384 publications receiving 11989 citations. Previous affiliations of Hong Zhang include Indiana University – Purdue University Indianapolis & ShanghaiTech University.

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LIN‐28 balances longevity and germline stem cell number in Caenorhabditis elegans through let‐7/AKT/DAF‐16 axis

TL;DR: The LIN‐28/let‐7/AKT/DAF‐16 axis delineated here is a program that plays an important role in balancing reproduction and somatic maintenance and their response to the environmental energy level—a central dogma of the ‘evolutionary optimization’ of resource allocation that modulates aging.
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Fluorophore-Dependent Cleavage of Disulfide Bond Leading to a Highly Selective Fluorescent Probe of Thioredoxin

TL;DR: A highly selective fluorescent probe for thioredoxin (Trx), a ubiquitous redox-regulating protein essentially involved in cell growth, differentiation and death, is reported, which displays multiple favorable properties, such as red emission, fast response and high fluorescence signal, which enabled the probe to readily image Trx functions in live cells and in vivo.
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Exosomes as drug carriers for clinical application.

TL;DR: This review focuses on the application of exosomes as nanocarriers and the current status of the application in cancer therapy, and the most promising candidates for targeted drug or gene delivery vehicles.
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Inhibition of Wnt signalling pathway by XAV939 enhances radiosensitivity in human cervical cancer HeLa cells.

TL;DR: It is suggested that blockage of the Wnt/β-catenin pathway effectively sensitizes HeLa cells to 12C6+ irradiation, and it may be a potential therapeutic approach in terms of increasing the clinical efficacy of 12C 6+ beams.