H
Hong Zhang
Researcher at Chinese Academy of Sciences
Publications - 482
Citations - 15856
Hong Zhang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Synthetic aperture radar & Autophagy. The author has an hindex of 52, co-authored 384 publications receiving 11989 citations. Previous affiliations of Hong Zhang include Indiana University – Purdue University Indianapolis & ShanghaiTech University.
Papers
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Journal ArticleDOI
Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates regulated exocytosis in tumorigenesis
Rachel E. Palmer,Sean Bong Lee,Jenise C. Wong,Paul A. Reynolds,Hong Zhang,Vivi Truong,Jonathan D. Oliner,William L. Gerald,Daniel A. Haber +8 more
TL;DR: BAIAP3 encodes a transcriptional target of an oncogenic fusion protein that implicates the regulated exocytotic pathway in cancer cell proliferation and dramatically enhances growth in low serum and colony formation in soft agar.
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Combining a single shot multibox detector with transfer learning for ship detection using sentinel-1 SAR images
TL;DR: Experimental results reveal that 1) transfer learning improves the detection accuracy and overall performance and reduces the false positives, and 2) compared with the faster RCNN and other SSD models, the SSD-512 model with transfer learning achieves the best overall performance, which demonstrates the effectiveness of the approach.
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ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress.
TL;DR: In this article, the authors showed that SARS-CoV-2 ORF3a, but not SARS CoV ORF 3a, promoted lysosomal exocytosis.
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Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy
Fan Wu,Yasunori Watanabe,Xiangyang Guo,Xin Qi,Peng Wang,Hongyu Zhao,Zheng Wang,Yuko Fujioka,Hui Zhang,Jin-Qi Ren,Tiancheng Fang,Yuxian Shen,Wei Feng,Junjie Hu,Nobuo N. Noda,Hong Zhang +15 more
TL;DR: The differential function of two ATG8 homologs in autophagy during C. elegans development is revealed, including structurally distinct substrate binding pockets that prefer different residues in the interacting LIR motif, thus influencing binding specificity.
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Phase Separation, Transition, and Autophagic Degradation of Proteins in Development and Pathogenesis.
Zheng Wang,Hong Zhang +1 more
TL;DR: Elucidation of the role of phase separation and transition in the degradation of disease-related protein condensates will provide insights into the molecular mechanism underlying the pathogenesis of various diseases.