H
Hui Kang
Researcher at Max Planck Society
Publications - 5
Citations - 1764
Hui Kang is an academic researcher from Max Planck Society. The author has contributed to research in topics: Paired-end tag & Regulation of gene expression. The author has an hindex of 4, co-authored 5 publications receiving 1649 citations. Previous affiliations of Hui Kang include Shanghai Jiao Tong University.
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Journal ArticleDOI
Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice
Shahaf Peleg,Farahnaz Sananbenesi,Athanasios Zovoilis,Susanne Burkhardt,Sanaz Bahari-Javan,Roberto Carlos Agis-Balboa,Perla Cota,Jessica Wittnam,Andreas Gogol-Doering,Lennart Opitz,Gabriella Salinas-Riester,Markus Dettenhofer,Hui Kang,Laurent Farinelli,Wei Chen,Andre Fischer +15 more
TL;DR: It is shown that memory disturbances in the aging brain of the mouse are associated with altered hippocampal chromatin plasticity, and data suggest that deregulated H4K12 acetylation may represent an early biomarker of an impaired genome-environment interaction in the Aging mouse brain.
Journal ArticleDOI
The Schistosoma japonicum genome reveals features of host-parasite interplay
Yan Zhou,Huajun Zheng,Yangyi Chen,Lei Zhang,Kai Wang,Jing Guo,Zhen Huang,Bo Zhang,Wei Huang,Ke Jin,Tonghai Dou,Masami Hasegawa,Li Wang,Yuan Zhang,Jie Zhou,Lin Tao,Zhiwei Cao,Yixue Li,Tomas Vinar,Brona Brejová,Daniel G. Brown,Ming Li,David J. Miller,David Blair,Yang Zhong,Zhu Chen,Feng Liu,Wei Hu,Zhi-Qin Wang,Qin-Hua Zhang,Huai-Dong Song,Sai-Juan Chen,Xue-Nian Xu,Bin Xu,Chuan Ju,Yucheng Huang,Paul J. Brindley,Donald P. McManus,Zheng Feng,Ze-Guang Han,Gang Lu,Shuang-Xi Ren,Y.S. Wang,Wenyi Gu,Hui Kang,Jie Chen,Xiaoyun Chen,Shuting Chen,Lijun Wang,Jie Yan,Biyun Wang,Xinyan Lv,Lei Jin,Bofei Wang,Shiyin Pu,Xiang-Lin Zhang,Wei Zhang,Qiuping Hu,Genfeng Zhu,Jun Wang,Jun Yu,Jing Wang,Huanming Yang,Zemin Ning,Matthew Beriman,Chia-Lin Wei,Yijun Ruan,Guoping Zhao,Shengyue Wang +68 more
TL;DR: The genome provides a global insight into the molecular architecture and host interaction of this complex metazoan pathogen, revealing that it can exploit host nutrients, neuroendocrine hormones and signalling pathways for growth, development and maturation.
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Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo
Guang-Biao Zhou,Guang-Biao Zhou,Hui Kang,Lan Wang,Li Gao,Ping Liu,Jun Xie,Feng-Xiang Zhang,Xiang-Qin Weng,Zhi-Xiang Shen,Jue Chen,Long-Jun Gu,Ming Yan,Dong-Er Zhang,Sai Juan Chen,Zhen-Yi Wang,Zhu Chen +16 more
TL;DR: The results suggest that oridonin may be a potential antileukemia agent that targets AE oncoprotein at residue D188 with low adverse effect, and may be helpful for the treatment of patients with t(8;21) AML.
Journal ArticleDOI
Breakpoint analysis of balanced chromosome rearrangements by next-generation paired-end sequencing
Wei Chen,Reinhard Ullmann,Claudia Langnick,Corinna Menzel,Zofia Wotschofsky,Hao Hu,Andreas Döring,Yuhui Hu,Hui Kang,Andreas Tzschach,Maria Hoeltzenbein,Heidemarie Neitzel,Susanne Markus,Eberhard Wiedersberg,Gerd Kistner,Conny M. A. van Ravenswaaij-Arts,Tjitske Kleefstra,Vera M. Kalscheuer,Hans-Hilger Ropers +18 more
TL;DR: The results show the feasibility of paired-end sequencing of systematic breakpoint mapping and gene finding in patients with disease-associated chromosome rearrangements.
adverse effects on t(8;21) leukemia in vitro and in vivo AML1-ETO fusion protein and shows potent antitumor activity with low Oridonin, a diterpenoid extracted from medicinal herbs, targets
Chen Zhu,Jue Chen,Long-Jun Gu,Ming Yan,Dong-Er Zhang,Sai Juan Chen,Guang-Biao Zhou,Hui Kang,Lan Wang,Ping Liu,Jun Xie,Feng-Xiang Zhang +11 more