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Ilaria Testa
Researcher at Royal Institute of Technology
Publications - 73
Citations - 3710
Ilaria Testa is an academic researcher from Royal Institute of Technology. The author has contributed to research in topics: RESOLFT & STED microscopy. The author has an hindex of 23, co-authored 65 publications receiving 3026 citations. Previous affiliations of Ilaria Testa include University of Genoa & Science for Life Laboratory.
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Journal ArticleDOI
Diffraction-unlimited all-optical imaging and writing with a photochromic GFP
Tim Grotjohann,Ilaria Testa,Marcel Leutenegger,Hannes Bock,Nicolai T. Urban,Flavie Lavoie-Cardinal,Katrin I. Willig,Christian Eggeling,Stefan Jakobs,Stefan W. Hell +9 more
TL;DR: An optical nanoscopy that records raw data images from living cells and tissues with low levels of light is demonstrated, facilitated by the generation of reversibly switchable enhanced green fluorescent protein (rsEGFP), a fluorescent protein that can be reversibly photoswitched more than a thousand times.
Journal ArticleDOI
Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration.
Andrea Palamidessi,Emanuela Frittoli,Massimiliano Garrè,Mario Faretta,Marina Mione,Ilaria Testa,Alberto Diaspro,Letizia Lanzetti,Giorgio Scita,Pier Paolo Di Fiore +9 more
TL;DR: It is demonstrated that a Rab5-to-Rac circuitry controls the morphology of motile mammalian tumor cells and primordial germinal cells during zebrafish development, suggesting that this circuitry is relevant for the regulation of migratory programs in various cells, in both in vitro settings and whole organisms.
Journal ArticleDOI
The 2015 super-resolution microscopy roadmap
Stefan W. Hell,Stefan W. Hell,Steffen J. Sahl,Mark Bates,Xiaowei Zhuang,Rainer Heintzmann,Rainer Heintzmann,Rainer Heintzmann,Martin J. Booth,Joerg Bewersdorf,Gleb Shtengel,Harald F. Hess,Philip Tinnefeld,Alf Honigmann,Stefan Jakobs,Ilaria Testa,Laurent Cognet,Brahim Lounis,Helge Ewers,Simon J. Davis,Christian Eggeling,David Klenerman,Katrin I. Willig,Giuseppe Vicidomini,Marco Castello,Alberto Diaspro,Thorben Cordes +26 more
TL;DR: Super-resolution optical microscopy is an important tool in a number of scientific disciplines including chemical, (bio)physical and biomedical research, particularly with respect to the study of living cells and organisms.
Journal ArticleDOI
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching
Tanja Brakemann,Andre C. Stiel,Gert Weber,Martin Andresen,Ilaria Testa,Tim Grotjohann,Marcel Leutenegger,Uwe Plessmann,Henning Urlaub,Christian Eggeling,Markus C. Wahl,Stefan W. Hell,Stefan Jakobs +12 more
TL;DR: A bright, monomeric, reversibly photoswitchable variant of GFP, Dreiklang, whose fluorescence excitation spectrum is decoupled from that for optical switching, enabling far-field fluorescence nanoscopy in living mammalian cells using both a coordinate-targeted and a stochastic single molecule switching approach.
Journal ArticleDOI
The 2015 super-resolution microscopy roadmap
Stefan W. Hell,Steffen J. Sahl,Mark Bates,Xiaowei Zhuang,Rainer Heintzmann,Martin J. Booth,Joerg Bewersdorf,Gleb Shtengel,Harald F. Hess,Philipp Tinnefeld,Alf Honigmann,Stefan Jakobs,Ilaria Testa,Laurent Cognet,Brahim Lounis,Helge Ewers,Simon J. Davis,Christian Eggeling,David Klenerman,Katrin I. Willig,Giuseppe Vicidomini,Marco Castello,Alberto Diaspro,Thorben Cordes,Steffen J. Sahl,Philip Tinnefeld,Katrin I. Willig +26 more
TL;DR: Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio) physical and biomedical research, particularly with respect to biomedical research.