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Inger Nennesmo
Researcher at Karolinska Institutet
Publications - 64
Citations - 2943
Inger Nennesmo is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Dermatomyositis & Polymyositis. The author has an hindex of 29, co-authored 57 publications receiving 2724 citations. Previous affiliations of Inger Nennesmo include Max Planck Society.
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A Pan‐European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats
Julie van der Zee,Ilse Gijselinck,Lubina Dillen,Tim Van Langenhove,Jessie Theuns,Sebastiaan Engelborghs,Stéphanie Philtjens,Mathieu Vandenbulcke,Kristel Sleegers,Anne Sieben,Anne Sieben,Veerle Bäumer,Githa Maes,Ellen Corsmit,Barbara Borroni,Alessandro Padovani,Silvana Archetti,Robert Perneczky,Janine Diehl-Schmid,Alexandre de Mendonça,Gabriel Miltenberger-Miltenyi,Sónia Pereira,José Pimentel,Benedetta Nacmias,Silvia Bagnoli,Sandro Sorbi,Caroline Graff,Caroline Graff,Huei-Hsin Chiang,Marie Westerlund,Raquel Sánchez-Valle,Albert Lladó,Ellen Gelpi,Isabel Santana,Maria Rosário Almeida,Beatriz Santiago,Giovanni B. Frisoni,Orazio Zanetti,Cristian Bonvicini,Matthis Synofzik,Walter Maetzler,Jennifer Müller vom Hagen,Ludger Schöls,Michael T. Heneka,Michael T. Heneka,Frank Jessen,Frank Jessen,Radoslav Matej,Eva Parobkova,Gabor G. Kovacs,Thomas Ströbel,Stayko Sarafov,Ivailo Tournev,Ivailo Tournev,Albena Jordanova,Adrian Danek,Thomas Arzberger,Gian Maria Fabrizi,Silvia Testi,Eric Salmon,Patrick Santens,Jean-Jacques Martin,Patrick Cras,Rik Vandenberghe,Peter Paul De Deyn,Marc Cruts,Christine Van Broeckhoven,Peter Paul De Deyn,Alfredo Ramirez,Delia Kurzwelly,Carmen Sachtleben,Wolfgang Mairer,Clara Firmo,Anna Antonell,José Luis Molinuevo,Anne Kinhult Ståhlbom,Håkan Thonberg,Inger Nennesmo,Anne Börjesson-Hanson,Valentina Bessi,Irene Piaceri,Maria Helena Ribeiro,Catarina R. Oliveira,João Massano,Carolina Garret,Paula Pires,Adrian Danel,Sergio Ferrari,Tiziana Cavallaro +88 more
TL;DR: In vitro reporter gene expression studies demonstrated significantly decreased transcriptional activity of C9orf72 with increasing number of normal repeat units, indicating that intermediate repeats might act as predisposing alleles and in favor of the loss‐of‐function disease mechanism.
Journal ArticleDOI
Alterations of mitochondrial function and correlations with personality traits in selected major depressive disorder patients
Ann Gardner,Anna L.V. Johansson,Rolf Wibom,Inger Nennesmo,Ulrika von Döbeln,Lars Hagenfeldt,Tore Hällström +6 more
TL;DR: Investigating mitochondrial function in selected depressed patients in search of an aetiological or pathophysiological factor common to both depression and physical symptoms suggested that mitochondrial dysfunction is associated with vulnerability to psychopathology in this selected patient group.
Journal ArticleDOI
Resolution of inflammation is altered in Alzheimer's disease
Xiuzhe Wang,Mingqin Zhu,Erik Hjorth,Veronica Cortés-Toro,Helga Eyjolfsdottir,Caroline Graff,Inger Nennesmo,Jan Palmblad,Maria Eriksdotter,Kumar Sambamurti,Jonathan M. Fitzgerald,Charles N. Serhan,Ann-Charlotte Granholm,Marianne Schultzberg +13 more
TL;DR: Resolution is the final stage of the inflammatory response, when restoration of tissue occurs and may lead to chronic inflammation, which is known as part of the pathology in the brain of individuals with Alzheimer's disease.
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A high incidence of disease flares in an open pilot study of infliximab in patients with refractory inflammatory myopathies
Maryam Dastmalchi,Cecilia Grundtman,Helene Alexanderson,Clio P. Mavragani,H Einarsdottir,S Barbasso Helmers,Kerstin Elvin,Mary K. Crow,Inger Nennesmo,Ingrid E. Lundberg +9 more
TL;DR: Infliximab treatment was not effective in refractory inflammatory myopathies, and activation of the type I IFN system in several cases, infliximab is not an alternative treatment in patients with treatment-resistant myositis.
Journal ArticleDOI
Neuron to neuron transmission of herpes simplex virus ☆: Transport of virus from skin to brainstem nuclei
TL;DR: The findings indicate that HSV spreads via axons, passes through a series of neurons and in this way can reach vital nuclei in the brainstem including monoaminergic neurons from the primary replication area in the lip.