Israel Liberzon

TL;DR: The findings link appraisal of negative affect with aberrant activation of the medial frontal cortex, while early sensory processing of this social cognitive task was linked with poor social function, reflecting either top-down or bottom-up influences.

TL;DR: The data suggest that different types of emotion regulation utilize overlapping circuits, but with some strategy specific activation, and that males and females showed opposing neural effects in prefrontal areas.

TL;DR: Two articles in this issue use different study designs and methods to reach the same goal: to understand the genetic basis of PTSD.

TL;DR: This test-of-concept pilot explored the hypothesis that there is a trauma-related subtype of HG characterized by high levels of dissociative symptoms and altered plasma concentrations of oxytocin, informed by a theory of posttraumatic Oxytocin dysregulation that posits altered oxytoc in function as a mechanism of gut smooth muscle peristalsis dysfunction.

TL;DR: Results suggested that PTSD patients who engage with emotional content as demonstrated by greater startle reactivity may be more likely to respond to PTSD treatment, and trauma-potentiated startle shows promise as an objective measure of psychophysiological responses involved in PTSD recovery.