I
Ivana Zlatanova
Researcher at French Institute of Health and Medical Research
Publications - 14
Citations - 527
Ivana Zlatanova is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Embryonic stem cell & Immunology. The author has an hindex of 7, co-authored 9 publications receiving 330 citations. Previous affiliations of Ivana Zlatanova include University of California, San Francisco & University of Paris.
Papers
More filters
Journal ArticleDOI
Intra-Cardiac Release of Extracellular Vesicles Shapes Inflammation Following Myocardial Infarction.
Xavier Loyer,Xavier Loyer,Ivana Zlatanova,Ivana Zlatanova,Cécile Devue,Cécile Devue,Min Yin,Min Yin,Kiave-Yune Howangyin,Kiave-Yune Howangyin,Phatchanat Klaihmon,Coralie L. Guerin,Marouane Kheloufi,Marouane Kheloufi,José Vilar,José Vilar,Konstantinos Zannis,Bernd K. Fleischmann,Do Won Hwang,Do Won Hwang,Jongmin Park,Hakho Lee,Philippe Menasché,Philippe Menasché,Jean-Sébastien Silvestre,Jean-Sébastien Silvestre,Chantal M. Boulanger +26 more
TL;DR: Coronary artery ligation in mice transiently increases the generation of cardiac EVs characterized as both exosomes and microvesicles, originating mainly from cardiomyocytes and endothelial cells, which regulate local inflammatory responses.
Journal ArticleDOI
Myeloid-Epithelial-Reproductive Receptor Tyrosine Kinase and Milk Fat Globule Epidermal Growth Factor 8 Coordinately Improve Remodeling After Myocardial Infarction via Local Delivery of Vascular Endothelial Growth Factor.
Kiave-Yune Howangyin,Ivana Zlatanova,Cristina Pinto,Anta Ngkelo,Clément Cochain,Marie Rouanet,José Vilar,Mathilde Lemitre,Christian Stockmann,Bernd K. Fleischmann,Ziad Mallat,Jean-Sébastien Silvestre +11 more
TL;DR: After myocardial infarction, Mertk- and Mfge8-expressing monocyte/macrophages synergistically engage the clearance of injured cardiomyocytes, favoring the secretion of VEGFA to locally repair the dysfunctional heart.
Journal ArticleDOI
Genetic and Pharmacological Inhibition of TREM-1 Limits the Development of Experimental Atherosclerosis
Jérémie Joffre,Stephane Potteaux,Lynda Zeboudj,Xavier Loyer,Amir Boufenzer,Ludivine Laurans,Bruno Esposito,Marie Vandestienne,Saskia C.A. de Jager,Carole Hénique,Ivana Zlatanova,Soraya Taleb,Patrick Bruneval,Alain Tedgui,Ziad Mallat,Sébastien Gibot,Hafid Ait-Oufella +16 more
TL;DR: It is proposed that TREM-1 activation orchestrates monocyte/macrophage proinflammatory responses and foam cell formation through coordinated and combined activation of CD36 and TLR4.
Journal ArticleDOI
Immune Modulation of Cardiac Repair and Regeneration: The Art of Mending Broken Hearts.
TL;DR: The present review summarizes the mounting evidence suggesting that the inflammatory response also guides the regenerative process following cardiac damage and focuses on the growing inflammatory intermediaries that have been recognized as essential player in heart regeneration.
Journal ArticleDOI
Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling.
Icía Santos-Zas,Jeremie Lemarié,Ivana Zlatanova,Marine Cachanado,Jean-Christophe Seghezzi,Benamer H,Pascal Goube,Marie Vandestienne,Raphael Cohen,Maya Ezzo,Vincent Duval,Yujiao Zhang,Jin-Bo Su,Alain Bizé,Lucien Sambin,Philippe Bonnin,Maxime Branchereau,Christophe Heymes,Corinne Tanchot,José Vilar,Clément Delacroix,Jean-Sébastien Hulot,Clément Cochain,Patrick Bruneval,Nicolas Danchin,Alain Tedgui,Ziad Mallat,Ziad Mallat,Tabassome Simon,Bijan Ghaleh,Jean-Sébastien Silvestre,Hafid Ait-Oufella +31 more
TL;DR: In this paper, the authors show that following acute myocardial infarction in mice, CD8+ T lymphocytes are recruited and activated in the ischemic heart tissue and release Granzyme B, leading to cardiomyocyte apoptosis, adverse ventricular remodeling and deterioration of myocardia.