J
Jack A. Roth
Researcher at University of Texas MD Anderson Cancer Center
Publications - 790
Citations - 55408
Jack A. Roth is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 110, co-authored 764 publications receiving 51306 citations. Previous affiliations of Jack A. Roth include University of Texas System & University of Texas at Austin.
Papers
More filters
Posted ContentDOI
Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
Yvonne A. Evrard,Anuj Srivastava,Jelena Randjelovic,Sasi Arunachalam,Carol J. Bult,Huiqin Chen,Lily Chen,Michael Davies,Sherri R. Davies,Brandi N. Davis-Dusenbery,Jack DiGiovanna,Li Ding,James H. Doroshow,Bingliang Fang,Christian Frech,Ramaswamy Govindan,Min Jin Ha,Meenhard Herlyn,Ryan Jeon,Andrew V. Kossenkov,Michael T. Lewis,Shunqiang Li,Michael Lloyd,Funda Meric-Bernstam,Nevena Miletic,Jeffrey A. Moscow,Steven B. Neuhauser,David A. Nix,Rajesh Patidar,Vito W. Rebecca,Peter N. Robinson,Jacqueline Rosains,Jack A. Roth,Isheeta Seth,Tamara Stankovic,Adam Stanojevic,Brian A. Van Tine,Alana L. Welm,Bryan E. Welm,Jayamanna Wickramasinghe,Xing Yi Woo,Min Xiao,Zi-Ming Zhao,Dennis A. Dean,Jeffrey S. Morris,Jeffrey H. Chuang +45 more
TL;DR: These studies show that PDX drug responses and sequence results are reproducible across diverse experimental protocols, and share the range of experimental procedures that maintained robustness, as well as standardized cloud-based workflows for PDX exome-seq and RNA-Seq analysis and for evaluating growth.
Journal ArticleDOI
Perioperative Outcomes for Stage I Non-Small Cell Lung Cancer: Differences Between Men and Women.
David B. Nelson,Danica J. Lapid,Kyle G. Mitchell,Arlene M. Correa,Wayne L. Hofstetter,Reza J. Mehran,David C. Rice,Boris Sepesi,Garrett L. Walsh,Ara A. Vaporciyan,Stephen G. Swisher,Jack A. Roth,Mara B. Antonoff +12 more
TL;DR: Women demonstrated an increased likelihood of being admitted after presenting to the ED within 30 days after discharge, indicating important differences between men and women in the short-term period after lobectomy.
Journal ArticleDOI
Immune responses to repetitive adenovirus-mediated gene transfer and restoration of gene expression by cyclophosphamide or etoposide.
Katsuyuki Hamada,Morito Sakaue,Asis K. Sarkar,Stepanie Buchl,William C. Satterfield,Michale E. Keeling,Jagannandha Sastry,Jack A. Roth,Michele Follen +8 more
TL;DR: It is suggested that repetitive gene expression by adenovirus-mediated transfer may be reduced by circulating neutralizing antibodies and could be restored by chronic low-dose treatment with cyclophosphamide or etoposide.
Journal ArticleDOI
Time Trends of Perioperative Outcomes in Early Stage Non-Small Cell Lung Cancer Resection Patients.
Jitesh B. Shewale,Arlene M. Correa,Eric L. Brown,Luis Leon-Novelo,Alan G. Nyitray,Mara B. Antonoff,Wayne L. Hofstetter,Reza J. Mehran,David C. Rice,Garrett L. Walsh,Jack A. Roth,Ara A. Vaporciyan,Stephen G. Swisher,Boris Sepesi +13 more
TL;DR: Predictors of pulmonary complications could be used to improve selection criteria for surgery and to reduce the incidence of pulmonary complication in patients undergoing resection for early-stage non-small cell lung cancer (NSCLC).
Journal ArticleDOI
A simple and efficient method for isolation of DNA fragments from agarose gel
Tapas Mukhopadhyay,Jack A. Roth +1 more
TL;DR: A simple method for isolation of purified DNA fragments from agarose gels that enables us to recover a high yield of intact pure DNA fragments of any size and is quick, efficient, and does not require expensive materials.