J
James B. Osborne
Researcher at Georgia Regents University
Publications - 2
Citations - 356
James B. Osborne is an academic researcher from Georgia Regents University. The author has contributed to research in topics: Interleukin 6 & Knockout mouse. The author has an hindex of 2, co-authored 2 publications receiving 327 citations.
Papers
More filters
Journal ArticleDOI
Angiotensin II hypertension is attenuated in interleukin-6 knockout mice.
Dexter L. Lee,LaShon Sturgis,Hicham Labazi,James B. Osborne,Cassandra Fleming,Jennifer S. Pollock,Marlina Manhiani,John D. Imig,Michael W. Brands +8 more
TL;DR: The approximately 30 mmHg greater ANG II hypertension in the WT mice suggests that IL-6 contributes significantly to ANG II-salt hypertension, and early separation in MAP, the albumin excretion data, and the rapid, post-ANG II recovery of MAP suggest an IL- 6-dependent mechanism that is independent of renal injury.
Journal ArticleDOI
Long-term outcome of early versus delayed rasagiline treatment in early Parkinson's disease.
Robert A. Hauser,Mark F. Lew,Howard I. Hurtig,William G. Ondo,Joanne Wojcieszek,Cheryl Fitzer-Attas,Frederick J. Marshall,Irenita Gardiner,Nancy Pearson,Debra Berry,Kathleen M. Shannon,Jean A. Jaglin,William G. Ondo,Christine Hunter,Cathy R. Anderson,Peter A. LeWitt,Patricia Kaminski,Dawn Miller,Maryan DeAngelis,Janis M. Miyasaki,Julie So,Lisa Johnston,Caroline M. Tanner,Tracy Stewart,Lisa Tagg,Sheila Everett,Georgia Germain,Mickie Welsh,Micki McCollister,Linda L. Mann,Carlos Singer,William C. Koller,William J. Weiner,Dinorah Bateman,Tilak Mendis,Melodie Moterson,Cynthia Alcorn-Costa,Keely Haas,Peggy Gray,Davoud Mohtat,Neila Mendis,Laura Sutherland,Howard H. Hurtig,Mary Lloyd,Mary Mathews,Robert Hauser,Lisa Gauger,Patricia Dyches,Cheryl Newcomb,Jean P. Hubble,Karen Betcher,Carolyn C. Weeks,Sandra K. Kostyk,Ali H. Rajput,Marlene Gerow,Linda Klassen,Marianne Ewasnishin,Lawrence I. Golb,Vanessa Patterson,Deborah L. Caputo,Patricia Seuffert,Rajesh Pahwa,Tamara Gales,Lorette J. Jenkins,Amy Parsons,Scott Cradr,Jovianna N. Wellinghoff,Shantelle Coe,Cheryl Armstrong,Connie Kawai,Katherine B. Hawthorne,Kellie Gelles,Xiaoming Lu,Suzanne W. Schuman,Cheryl Cooper,Kenneth Marek,Barbara Fussell,Karen Caplan,Erica Barnabei,Karen Stavris,Kapil D. Sethi,J. Carpenter,James B. Osborne,Shoba Narayan,K. Ligon,Eric Molho,Sharon Evans,Jacqueline Nash,Diane Brown,Mark Stacy,Kelli Williamson,Peter Novak,Robert G. Feldman,Cathi A. Thomas,W.R. Wayne Martin,Pam King,Germanine McInnes,Shaunna Caouette,Jo Belden,Andew Feigin,Jean Ayan,Barbara Shannon,Charles H. Adler,Stephanie Newman,Teri Radam,Myrna Schear,Naomi Santoni,Sharon Wortzel,Nancy Saton,Paul J. Tuite,Susan Rolandelli,Jody Lowery,Brenda Ebbitt,Adrienne Baranauskas,Michael J. Aminoff,Mirann DiMinno,Jessie Roth,Tracey Borst,Julie Hevezi,Carolyn Deloa,Tracey Tam,Anita Lopez,John M. Bertoni,Larisa I. Skrypnik,Carolyn Peterson,Mark Forrest Gordon,Roberta Winnick,Sharyn Parness,Joanne Hamann,Vincent Calabrese,Peggy Roberge,Paul Atchison,Cathy W. Allen,Susan Rolli,Arif Dalvi,Un Jung Kang,Judy Richman,Shirley Uy +137 more
TL;DR: Compared to delayed start, early initiation of rasagiline provided long‐term clinical benefit, even in the face of treatment with other dopaminergic agents.