H
Howard I. Hurtig
Researcher at University of Pennsylvania
Publications - 142
Citations - 27820
Howard I. Hurtig is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Dementia & Parkinson's disease. The author has an hindex of 68, co-authored 140 publications receiving 24232 citations. Previous affiliations of Howard I. Hurtig include Graduate Hospital & Avid Radiopharmaceuticals.
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Journal ArticleDOI
Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.
Christopher G. Goetz,Barbara C. Tilley,Stephanie R. Shaftman,Glenn T. Stebbins,Stanley Fahn,Pablo Martinez-Martin,Werner Poewe,Cristina Sampaio,Matthew B. Stern,Richard Dodel,Bruno Dubois,Robert G. Holloway,Joseph Jankovic,Jaime Kulisevsky,Anthony E. Lang,Andrew J. Lees,Sue Leurgans,Peter A. LeWitt,David L. Nyenhuis,C. Warren Olanow,Olivier Rascol,Anette Schrag,Jeanne A. Teresi,Jacobus J. van Hilten,Nancy R. LaPelle,Pinky Agarwal,Saima Athar,Yvette Bordelan,Helen Bronte-Stewart,Richard Camicioli,Kelvin L. Chou,Wendy Cole,Arif Dalvi,Holly Delgado,Alan Diamond,Jeremy P.R. Dick,John E. Duda,Rodger J. Elble,Carol Evans,V. G. H. Evidente,Hubert H. Fernandez,Susan H. Fox,Joseph H. Friedman,Robin D. Fross,David A. Gallagher,Deborah A. Hall,Neal Hermanowicz,Vanessa K. Hinson,Stacy Horn,Howard I. Hurtig,Un Jung Kang,Galit Kleiner-Fisman,Olga Klepitskaya,Katie Kompoliti,Eugene C. Lai,Maureen L. Leehey,Iracema Leroi,Kelly E. Lyons,Terry McClain,Steven W. Metzer,Janis M. Miyasaki,John C. Morgan,Martha Nance,Joanne Nemeth,Rajesh Pahwa,Sotirios A. Parashos,Jay S. Schneider,Kapil D. Sethi,Lisa M. Shulman,Andrew Siderowf,Monty Silverdale,Tanya Simuni,Mark Stacy,Robert Malcolm Stewart,Kelly L. Sullivan,David M. Swope,Pettaruse M. Wadia,Richard Walker,Ruth H. Walker,William J. Weiner,Jill Wiener,Jayne R. Wilkinson,Joanna M. Wojcieszek,Summer C. Wolfrath,Frederick Wooten,Allen Wu,Theresa A. Zesiewicz,Richard M. Zweig +87 more
TL;DR: The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD.
Journal ArticleDOI
MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging
TL;DR: The frequently observed "halo" of periventricular hyperintensity in Alzheimer's disease may be of diagnostic importance and high-signal abnormalities in specific cortical regions are likely to reflect disease processes localized to those structures.
Journal Article
MR Signal Abnormalities at 1.5 T in Alzheimer's Dementia and Normal Aging
TL;DR: The type, frequency, and extent of MR signal abnormalities in Alzheimer9s disease and normal aging are a subject of controversy as mentioned in this paper, and the most commonly observed "halo" of periventricular hyperintensity in Alzheimer 9s disease may be of diagnostic importance.
Journal ArticleDOI
Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions
Benoit I. Giasson,John E. Duda,Ian V.J. Murray,Qiping Chen,José M. Souza,Howard I. Hurtig,Harry Ischiropoulos,John Q. Trojanowski,Virginia M.-Y. Lee +8 more
TL;DR: The selective and specific nitration of alpha-synuclein in these disorders provides evidence to directly link oxidative and nitrative damage to the onset and progression of neurodegenerative synucleinopathies.
Journal ArticleDOI
Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson’s disease
Howard I. Hurtig,John Q. Trojanowski,James E. Galvin,Douglas C. Ewbank,Marie L. Schmidt,Virginia M.-Y. Lee,Christopher M. Clark,Guila Glosser,M.B. Stern,Steven M. Gollomp,Steven E. Arnold +10 more
TL;DR: CLBs detected by α-synuclein antibodies in patients with PD are a more sensitive and specific correlate of dementia than the presence of Alzheimer’s pathology, which was present in a minority of the cases in this series.