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Irenita Gardiner
Researcher at University of Rochester
Publications - 13
Citations - 3069
Irenita Gardiner is an academic researcher from University of Rochester. The author has contributed to research in topics: Randomized controlled trial & Epilepsy. The author has an hindex of 12, co-authored 13 publications receiving 2732 citations. Previous affiliations of Irenita Gardiner include University of Rochester Medical Center.
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Journal ArticleDOI
Early Surgical Therapy for Drug-Resistant Temporal Lobe Epilepsy: A Randomized Trial
Jerome Engel,Michael P. McDermott,Samuel Wiebe,John T. Langfitt,John M. Stern,Sandra Dewar,Michael R. Sperling,Irenita Gardiner,Giuseppe Erba,Itzhak Fried,Margaret Jacobs,Harry V. Vinters,Scott Mintzer,Karl Kieburtz +13 more
TL;DR: Whether surgery soon after failure of 2 antiepileptic drug (AED) trials is superior to continued medical management in controlling seizures and improving quality of life (QOL) is sought and among patients with newly intractable disabling MTLE, resective surgery plus AED treatment resulted in a lower probability of seizures during year 2 of follow-up than continued AEDtreatment alone.
Journal Article
Pramipexole vs Levodopa as initial treatment for Parkinson disease: A randomized controlled trial
Robert G. Holloway,Ira Shoulson,K. Kieburtz,Michael P. McDermott,Pierre N. Tariot,Cornelia Kamp,Denni Day,Aileen Shinaman,S. Fahn,Anthony E. Lang,Kenneth Marek,John Seibyl,W. Weiner,M. Welsh,R. Pahwa,S. Coe,L. Barclay,L. Sutherland,K. Hildebrand,J. Hubble,C. Weeks,P. LeWitt,J. Miyasaki,J. Duff,E. Sime,O. Suchowersky,Mark Stacy,M. Kurth,M. Brewer,M. Harrigan,D. S. Russell,B. Fussell,B. Ford,S. Dillon,J. Hammerstad,C. Stone,D. Riley,P. Rainey,David G. Standaert,M. Tennis,F. Wooten,E. Rost-ruffner,S. Factor,D. Brown,Joseph Jankovic,F. Atassi,Roger Kurlan,Irenita Gardiner,M. Panisset,D. Amyot,J. Hall,A. Rajput,Theresa Shirley,Robert L. Rodnitzky,J. Dobson,C. Shults,D. Fontaine,C. Waters,S. Schuman,R. Pfeiffer,Shirley A. Rast,B. Pfeiffer,Alicia Brocht,Cindy Casaceli,Susan Daigneault,Karen Hodgeman,K. Honsinger,C. O'Connell,Arthur Watts +68 more
TL;DR: Initial pramipexole treatment resulted in significantly less development of wearing off, dyskinesias, or on-off motor fluctuations compared with levodopa (51%) (hazard ratio, 0.45; 95% confidence interval [CI], 0.66), and the mean improvement in total UPDRS score from baseline to 23.5 months was greater in thelevodopa group than in the pramipingxole group (9.5 points; P<.001).
Journal ArticleDOI
A controlled trial of rasagiline in early Parkinson disease: The tempo study
Andrew Siderowf,Matthew B. Stern,Ira Shoulson,Karl Kieburtz,David Oakes,Denni Day,Aileen Shinaman,Sandra Plumb,Stanley Fahn,Karen Blindauer,Mark F. Lew,Howard I. Hurtig,Mary Lloyd,Robert A. Hauser,Lisa Gauger,Lawrence I. Golbe,Joanne Wojcieszek,Joann Belden,Andrew Feigin,Mary Lou Klimek,Barbara Shannon,William G. Ondo,Christine Hunter,Vincent Calabrese,Paul Atchison,Cathy W. Allen,Frederick J. Marshall,Debra Berry,Irenita Gardiner,Janis M. Miyasaki,Luisa Del Rizzo,Tilak Mendis,Neila Mendis,Peggy Gray,Jean P. Hubble,Karen Betcher,Rajesh Pahwa,Eric Molho,Diane Brown,Lisa M. Shulman,Ali H. Rajput,Marianne Ewanishin,Mark Stacy,Kelli Williamson,John M. Bertoni,Carolyn Peterson,Paul J. Tuite,Brenda Ebbitt,Kathleen M. Shannon,Jean A. Jaglin,Caroline M. Tanner,Kenneth Marek,Karen Stavris,Michael J. Aminoff,Mariann DiMinno,Glenna A. Dowling,Un Jung Kang,Judy Richman,Kapil D. Sethi,W.R. Wayne Martin,Pamela King,Germaine McInnes,Charles H. Adler,Peter A. LeWitt,Maryan DeAngelis,Myrna Schear,Mark Forrest Gordon,Roberta Winnick,Robert G. Feldman,Cathi A. Thomas,Kelly M. Conn,Alicia Brocht,Chris Chadwick,Jeannette Connolly,Susan Daigneault,Shirley Eberly,Janice Bausch,Lee Josephson,Rosemary Oliva,Steven R. Schwid,Anthony E. Lang,Christopher Cox,Carrie Irvine,John G. Nutt,William B. White,Sheila Oren,Ruth Levy,Eli Eyal,David Ladkani,Wayne Houck +89 more
TL;DR: Rasagiline is effective as monotherapy for patients with early PD and the 2 dosages in this trial were both effective relative to placebo.
Journal ArticleDOI
Early Surgical Therapy for Drug-Resistant Temporal Lobe Epilepsy: A Randomized Trial
Jerome Engel,Michael P. McDermott,Samuel Wiebe,John T. Langfitt,John M. Stern,Sandra Dewar,Michael R. Sperling,Irenita Gardiner,Giuseppe Erba,Itzhak Fried,Margaret Jacobs,Harry V. Vinters,Scott Mintzer,Karl Kieburtz +13 more
Journal ArticleDOI
Predictors of nursing home placement in Huntington disease
Vicki L. Wheelock,Teresa Tempkin,Karen Marder,M. Nance,M. Nance,Richard H. Myers,Hongwei Zhao,Elise Kayson,Constance Orme,Ira Shoulson,Phillipa Hedges,Elizabeth McCusker,Samantha Pearce,Ronald Trent,David A. Abwender,Peter Como,Irenita Gardiner,Charlyne Hickey,Karl Kieburtz,Frederick J. Marshall,Nancy Pearson,Carol Zimmerman,Elan D. Louis,Carol Moskowitz,Carmen Polanco,Naomi Zubin,Catherine Brown,Jill Burke-Holder,Mark Guttman,Sandra Russell,Dwight J. Stewart,Jackie Thomson,Daniel S. Sax,Marie Saint-Hilaire,Jackie Gray,Cindy Hunter,Nanette Mercado,Eric Siemers,Joanne Wojeieszek,Ted M. Dawson,Elizabeth Leritz,Adam Rosenblatt,M. Sherr,Candace Young,Tetsuo Ashizawa,J. Beach,Joseph Jankovic,Jeana Jaglin,Kathleen M. Shannon,Anders Lundin,Kathleen Francis,Kim Lane,Alexander P. Auchus,J. Timothy Greenamyre,Steven M. Hersch,Randi Jones,David Olson,Jang Ho John Cha,Merit Cudkowicz,Walter J. Koroshetz,John B. Penney,Greg Rudolf,Paula Sexton,Anne B. Young,Roger L. Albin,Kristine Wernette,Donald S. Higgins,Carson Reider,Vicki Hunt,Francis O. Walker,Robert Hauscr,Juan Sanchez-Ramos,Audrey Walker,Carol Pantello,Gina Rohs,Oksana Suchowersky,Kerry Duncan,Lauren Seeberger,Jody Corey-Bloom,Jane S. Paulsen,Michael R. Swenson,Neal R. Swerdlow,W.R. Wayne Martin,Marguerite Wieler,Alicia Facca,Gustavo Rey,William Weiner,Charles A. Adler,John Caviness,Cindy Lied,Stephanie Newman,Andrew Feigin,Jennifer Mazurkiewicz,Karen Caplan,Janet S. Cellar,Kenneth Marck,Michael R. Hayden,Lynn A. Raymond,Leon S. Dure,Jane B. Lane +99 more
TL;DR: Institutionalized patients with HD are more motorically, psychiatrically, and behaviorally impaired than their counterparts living at home, and treatment strategies that delay the progression of motor dysfunction in HD may postpone the need for institutionalization.