J
Jamie Near
Researcher at Douglas Mental Health University Institute
Publications - 102
Citations - 3883
Jamie Near is an academic researcher from Douglas Mental Health University Institute. The author has contributed to research in topics: Medicine & Glutamate receptor. The author has an hindex of 28, co-authored 86 publications receiving 2823 citations. Previous affiliations of Jamie Near include University of Oxford & McGill University.
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Journal ArticleDOI
Relationship between physiological measures of excitability and levels of glutamate and GABA in the human motor cortex
Charlotte J. Stagg,Sven Bestmann,A O Constantinescu,A O Constantinescu,L Moreno Moreno,C Allman,Ralf Mekle,Ralf Mekle,Mark W. Woolrich,Jamie Near,Heidi Johansen-Berg,John C. Rothwell +11 more
TL;DR: A relationship was found between MRS‐assessed GABA and a TMS protocol with less clearly understood physiological underpinnings that may reflect extrasynaptic GABA tone, suggesting that MRS measures of glutamate do reflect glutamatergic activity.
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Advanced processing and simulation of MRS data using the FID appliance (FID-A)-An open source, MATLAB-based toolkit.
TL;DR: A new toolkit for simulation and processing of magnetic resonance spectroscopy data is introduced, and some of its novel features are demonstrated.
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Frequency and phase drift correction of magnetic resonance spectroscopy data by spectral registration in the time domain
Jamie Near,Richard A.E. Edden,Christopher John Evans,R Paquin,Ashley D. Harris,Peter Jezzard +5 more
TL;DR: A new method is presented for estimating and correcting frequency and phase drifts in in vivo MRS data that avoids artifactual broadening of spectral peaks, distortion of spectral lineshapes, and a reduction in signal‐to‐noise ratio (SNR).
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Modulation of GABA and resting state functional connectivity by transcranial direct current stimulation
TL;DR: Although the previously reported findings that anodal tDCS reduces GABA concentration and increases functional connectivity in the stimulated motor cortex are confirmed, these changes are not correlated, suggesting they may be driven by distinct underlying mechanisms.
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Baseline GABA concentration and fMRI response
TL;DR: These findings demonstrate that both the dominant BOLD fMRI contrast, as well as other emerging MR hemodynamic contrasts, have signal variations that are linked to baseline GABA levels.