J
Javier DeFelipe
Researcher at Technical University of Madrid
Publications - 350
Citations - 23301
Javier DeFelipe is an academic researcher from Technical University of Madrid. The author has contributed to research in topics: Neocortex & Dendritic spine. The author has an hindex of 76, co-authored 327 publications receiving 20464 citations. Previous affiliations of Javier DeFelipe include Spanish National Research Council & University of California, Irvine.
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Journal ArticleDOI
Size, Shape, and Distribution of Multivesicular Bodies in the Juvenile Rat Somatosensory Cortex: A 3D Electron Microscopy Study.
TL;DR: The sizes of MVBs follow a lognormal distribution, with differences across cortical layers and cellular compartments, and the mean volume of dendritic MVBs is more than twice as large as the volume of axonic MVBs.
Ups and downs in the genesis of cortical computation
Yves Frégnac,M. Blatow,Jean-Pierre Changeux,Javier DeFelipe,Henry Markram,Anders Lansner,Wolfgang Maass,D. A. McCormick,C. M. Michel,Hannah Monyer,E. Yuste R. Szathmáry +10 more
Journal ArticleDOI
Musical Representation of Dendritic Spine Distribution: A New Exploratory Tool
TL;DR: It is demonstrated that audio analysis of spiny dendrites with apparently similar morphology may “sound” quite different, revealing anatomical substrates that are not apparent from simple visual inspection.
Journal ArticleDOI
3D Analysis of the Synaptic Organization in the Entorhinal Cortex in Alzheimer's Disease.
Marta Dominguez-Alvaro,M. Montero-Crespo,M. Montero-Crespo,Lidia Blazquez-Llorca,Lidia Blazquez-Llorca,Lidia Blazquez-Llorca,S Plaza-Alonso,S Plaza-Alonso,Nicolás Cano-Astorga,Nicolás Cano-Astorga,Javier DeFelipe,Javier DeFelipe,Lidia Alonso-Nanclares +12 more
TL;DR: In this article, the authors performed 3D ultrastructural analyses of synapses using Focused Ion Beam/Scanning Electron Microscopy (FIB/SEM) to examine possible alterations related to AD.
Posted ContentDOI
A calcium-based plasticity model predicts long-term potentiation and depression in the neocortex
Giuseppe Chindemi,Marwan Abdellah,Oren Amsalem,Ruth Benavides-Piccione,Ruth Benavides-Piccione,Vincent Delattre,Michael Doron,András Ecker,James G. King,Pramod Kumbhar,Caitlin Monney,Rodrigo Perin,Christian Rössert,W.A.H. Van Geit,Javier DeFelipe,Javier DeFelipe,Michael Graupner,Idan Segev,Henry Markram,Eilif Muller +19 more
TL;DR: It is proposed that a similar set of plasticity mechanisms is shared by seemingly very different neocortical connections and that only a small number of targeted experiments is required for generating a complete map of synaptic plasticity dynamics in the neocortex.