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Javier DeFelipe

Researcher at Technical University of Madrid

Publications -  350
Citations -  23301

Javier DeFelipe is an academic researcher from Technical University of Madrid. The author has contributed to research in topics: Neocortex & Dendritic spine. The author has an hindex of 76, co-authored 327 publications receiving 20464 citations. Previous affiliations of Javier DeFelipe include Spanish National Research Council & University of California, Irvine.

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Selective presence of a giant saccular organelle in the axon initial segment of a subpopulation of layer V pyramidal neurons.

TL;DR: The results indicate the involvement of the GSO in the regulation of Ca2+ levels in the AIS in a particular subpopulation of layer V neurons that give rise to subcortical non-thalamic descending projections.
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Selective effects of Δ9-tetrahydrocannabinol on medium spiny neurons in the striatum

TL;DR: Results seem to indicate that THC could induce structural plasticity alterations in the circuits involving pDMS MSNs, which is thought to mediate long-lasting changes in behaviour.
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3D Ultrastructural Study of Synapses in the Human Entorhinal Cortex.

TL;DR: The present work constitutes a detailed description of the synaptic organization of the human EC, which is a necessary step to better understand the functional organization of this region in both health and disease.
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Dendritic spines are lost in clusters in Alzheimer's disease.

TL;DR: In this article, the authors used graph-theory approaches to compare the distribution of dendritic spines from neurons with and without tau pathology in individuals with Alzheimer's disease.