J
Jeremiah J. Faith
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 112
Citations - 21045
Jeremiah J. Faith is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Gut flora. The author has an hindex of 35, co-authored 85 publications receiving 16852 citations. Previous affiliations of Jeremiah J. Faith include Cold Spring Harbor Laboratory & Boston University.
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Journal ArticleDOI
Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice.
Graham J. Britton,Eduardo J. Contijoch,Ilaria Mogno,Olivia H. Vennaro,Sean R. Llewellyn,Ruby Ng,Zhihua Li,Arthur Mortha,Arthur Mortha,Miriam Merad,Anuk Das,Dirk Gevers,Dermot P.B. McGovern,Namita Singh,Jonathan Braun,Jonathan P. Jacobs,Jose C. Clemente,Ari Grinspan,Bruce E. Sands,Jean-Frederic Colombel,Marla Dubinsky,Jeremiah J. Faith +21 more
TL;DR: An impact on intestinal Th17 and ROR&ggr;t+ regulatory T cell compartments emerges as a unifying feature of IBD microbiotas, suggesting a general mechanism for microbial contribution to IBD pathogenesis.
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Specific bacteria and metabolites associated with response to fecal microbiota transplantation in patients with ulcerative colitis.
Sudarshan Paramsothy,Shaun Nielsen,Michael A. Kamm,Nandan P. Deshpande,Jeremiah J. Faith,Jose C. Clemente,Ramesh Paramsothy,Alissa Walsh,Johan van den Bogaerde,Douglas Samuel,Rupert W. Leong,Susan J. Connor,Watson Ng,Enmoore Lin,Thomas J. Borody,Marc R. Wilkins,Jean-Frederic Colombel,Hazel M. Mitchell,Nadeem O. Kaakoush +18 more
TL;DR: FMT increased microbial diversity and altered composition, based on analyses of colon and fecal samples collected before vs after FMT, and associated specific bacteria and metabolic pathways with induction of remission.
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Reverse-engineering transcription control networks
TL;DR: The algorithms for reverse-engineering transcription control networks are classified into two general strategies: physical modeling and influence modeling, and the biological and computational principles underlying each strategy are discussed.
Journal ArticleDOI
Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice
Sean R. Llewellyn,Graham J. Britton,Eduardo J. Contijoch,Olivia H. Vennaro,Arthur Mortha,Jean-Frederic Colombel,Ari Grinspan,Jose C. Clemente,Miriam Merad,Jeremiah J. Faith +9 more
TL;DR: In this paper, the effects of different dietary components and the gut microbiota on mice with and without DSS-induced colitis were analyzed, and the authors found complex mixtures of nutrients affect intestinal permeability, gut microbial density, and development of intestinal inflammation.
Journal ArticleDOI
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome
Aleksey Chudnovskiy,Arthur Mortha,Veronika Kana,Andrea Kennard,Juan David Ramírez,Juan David Ramírez,Adeeb Rahman,Romain Remark,Ilaria Mogno,Ruby Ng,Sasha Gnjatic,El-ad David Amir,Alexander Solovyov,Benjamin Greenbaum,Jose C. Clemente,Jeremiah J. Faith,Yasmine Belkaid,Michael E. Grigg,Miriam Merad +18 more
TL;DR: It is shown that the protozoan Tritrichomonas musculis activates the host epithelial inflammasome to induce IL-18 release, which increases mucosal host defenses at the cost of an increased risk of inflammatory disease.