J
Jeremiah J. Faith
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 112
Citations - 21045
Jeremiah J. Faith is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Gut flora. The author has an hindex of 35, co-authored 85 publications receiving 16852 citations. Previous affiliations of Jeremiah J. Faith include Cold Spring Harbor Laboratory & Boston University.
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Journal ArticleDOI
Challenges in IBD Research: Preclinical Human IBD Mechanisms.
Theresa T. Pizarro,Thaddeus S. Stappenbeck,Florian Rieder,Michael J. Rosen,Jean-Frederic Colombel,Mark Donowitz,Jennifer E. Towne,Sarkis K. Mazmanian,Jeremiah J. Faith,Richard A. Hodin,Wendy S. Garrett,Alessandro Fichera,Lisa S. Poritz,Constanza J. Cortes,Nataly Shtraizent,Gerard Honig,Scott B. Snapper,Andrés Hurtado-Lorenzo,Nita H. Salzman,Eugene B. Chang +19 more
TL;DR: The prioritization of reverse translation studies is proposed in which clinical observations are the foundation for experimental IBD research in the lab, and for the identification of new therapeutic targets and biomarkers, and the use of human samples in validating basic research findings and development of precision medicine solutions.
Journal ArticleDOI
Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19.
Graham J. Britton,Alice Chen-Liaw,Francesca Cossarini,Alexandra E. Livanos,Matthew P. Spindler,Tamar Plitt,Joseph Eggers,Ilaria Mogno,Ana S. Gonzalez-Reiche,Sophia Siu,Michael Tankelevich,Lauren Tal Grinspan,Rebekah E. Dixon,Divya Jha,Adriana van de Guchte,Zenab Khan,Gustavo Martinez-Delgado,Fatima Amanat,Daisy A. Hoagland,Benjamin R. tenOever,Marla Dubinsky,Miriam Merad,Harm van Bakel,Florian Krammer,Gerold Bongers,Saurabh Mehandru,Jeremiah J. Faith +26 more
TL;DR: In this article, the authors measured cytokines, inflammatory markers, viral RNA, microbiome composition, and antibody responses in stool samples from a cohort of 44 hospitalized COVID-19 patients.
Journal ArticleDOI
Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23.
Zhengxiang He,Lili Chen,Jovani Catalan-Dibene,Gerold Bongers,Jeremiah J. Faith,Chalada Suebsuwong,Robert J. DeVita,Zeli Shen,James G. Fox,Juan J. Lafaille,Glaucia C. Furtado,Sergio A. Lira +11 more
TL;DR: This paper showed that the azo dyes Red 40 and Yellow 6, the most abundant food colorants in the world, can trigger an IBD-like colitis in mice conditionally expressing IL-23, or in two additional animal models in which IL23 expression was augmented.
Journal ArticleDOI
Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes.
Varun Aggarwala,Ilaria Mogno,Zhihua Li,Chao Yang,Graham J. Britton,Alice Chen-Liaw,Josephine Mitcham,Gerold Bongers,Dirk Gevers,Jose C. Clemente,Jean-Frederic Colombel,Ari Grinspan,Jeremiah J. Faith +12 more
TL;DR: In this article, a collection of >1,000 different bacterial strains that were cultured from the fecal samples of 22 FMT donors and recipients was assembled and a statistical approach named Strainer was developed for the detection and tracking of bacterial strains from metagenomic sequencing data.
Posted ContentDOI
Gastrointestinal involvement attenuates COVID-19 severity and mortality
Alexandra E. Livanos,Divya Jha,Francesca Cossarini,Ana S. Gonzalez-Reiche,Minami Tokuyama,Teresa Aydillo,Tommaso Lorenzo Parigi,Irene Ramos,Katie A. Dunleavy,Brian T. Lee,Rebekah E. Dixon,Steven T. Chen,Gustavo Martinez-Delgado,Satish Nagula,Huaibin M. Ko,Benjamin S. Glicksberg,Girish N. Nadkarni,Elisabet Pujadas,Jason Reidy,Steven Naymagon,Ari Grinspan,Jawad Ahmad,Michael Tankelevich,Ronald E. Gordon,Keshav Sharma,Jane Houldsworth,Graham J. Britton,Alice Chen-Liaw,Matthew P. Spindler,Tamar Plitt,Pei Wang,Andrea Cerutti,Jeremiah J. Faith,Jean-Frederic Colombel,Ephraim Kenigsberg,Carmen Argmann,Miriam Merad,Sacha Gnjatic,Noam Harpaz,Silvio Danese,Carlos Cordon-Cardo,Adeeb Rahman,Nikhil A. Kumta,Alessio Aghemo,Francesca Petralia,Harm van Bakel,Adolfo García-Sastre,Saurabh Mehandru +47 more
TL;DR: The role of the GI tract in attenuating SARS-CoV-2-associated inflammation with related mortality benefit is highlighted and organ-level heterogeneity in disease pathogenesis is drawn attention.