J
Jeremy Bellay
Researcher at University of Minnesota
Publications - 15
Citations - 3134
Jeremy Bellay is an academic researcher from University of Minnesota. The author has contributed to research in topics: Synthetic genetic array & Gene. The author has an hindex of 10, co-authored 15 publications receiving 2920 citations. Previous affiliations of Jeremy Bellay include University of Maryland, College Park.
Papers
More filters
Journal ArticleDOI
The genetic landscape of a cell.
Michael Costanzo,Anastasia Baryshnikova,Jeremy Bellay,Yungil Kim,Eric D. Spear,Carolyn S. Sevier,Huiming Ding,Judice L. Y. Koh,Kiana Toufighi,Sara Mostafavi,Jeany Prinz,Robert P. St.Onge,Benjamin VanderSluis,Taras Makhnevych,Franco J. Vizeacoumar,Solmaz Alizadeh,Sondra Bahr,Renee L. Brost,Yiqun Chen,Murat Cokol,Raamesh Deshpande,Zhijian Li,Zhen Yuan Lin,Wendy Liang,Michaela Marback,Jadine Paw,Bryan Joseph San Luis,Ermira Shuteriqi,Amy Hin Yan Tong,Nydia Van Dyk,Iain M. Wallace,Joseph Whitney,Matthew T. Weirauch,Guoqing Zhong,Hongwei Zhu,Walid A. Houry,Michael Brudno,Sasan Ragibizadeh,Balázs Papp,Csaba Pál,Frederick P. Roth,Guri Giaever,Corey Nislow,Olga G. Troyanskaya,Howard Bussey,Gary D. Bader,Anne-Claude Gingras,Quaid Morris,Philip M. Kim,Chris A. Kaiser,Chad L. Myers,Brenda J. Andrews,Charles Boone +52 more
TL;DR: A network based on genetic interaction profiles reveals a functional map of the cell in which genes of similar biological processes cluster together in coherent subsets, and highly correlated profiles delineate specific pathways to define gene function.
Journal ArticleDOI
Systematic exploration of essential yeast gene function with temperature-sensitive mutants
Zhijian Li,Franco J. Vizeacoumar,Sondra Bahr,Jingjing Li,Jonas Warringer,Frederick S. Vizeacoumar,Renqiang Min,Benjamin VanderSluis,Jeremy Bellay,Michael Devit,James A. Fleming,Andrew D. Stephens,Julian Haase,Zhen Yuan Lin,Anastasia Baryshnikova,Hong Lu,Zhun Yan,Ke Jin,Sarah L. Barker,Alessandro Datti,Alessandro Datti,Guri Giaever,Corey Nislow,Chris Bulawa,Chad L. Myers,Michael Costanzo,Anne-Claude Gingras,Zhaolei Zhang,Anders Blomberg,Kerry Bloom,Brenda J. Andrews,Charles Boone +31 more
TL;DR: This mutant collection should facilitate a wide range of systematic studies aimed at understanding the functions of essential genes, including roles for cohesin and condensin genes in spindle disassembly.
Journal ArticleDOI
Bringing order to protein disorder through comparative genomics and genetic interactions
Jeremy Bellay,Sangjo Han,Magali Michaut,TaeHyung Kim,Michael Costanzo,Brenda J. Andrews,Charles Boone,Gary D. Bader,Chad L. Myers,Philip M. Kim +9 more
TL;DR: The clear and distinct functional association of flexible and constrained disorder will allow for new approaches and more specific algorithms for disorder detection in a functional context and demonstrate clear evolutionary selection of protein disorder with little selection on primary structure.
Journal ArticleDOI
Genetic interactions reveal the evolutionary trajectories of duplicate genes.
Benjamin VanderSluis,Jeremy Bellay,Gabriel Musso,Michael Costanzo,Balázs Papp,Franco J. Vizeacoumar,Anastasia Baryshnikova,Brenda J. Andrews,Charles Boone,Chad L. Myers +9 more
TL;DR: It is shown that duplicate genes exhibit fewer genetic interactions than other genes because they tend to buffer one another functionally, whereas observed interactions are non‐overlapping and reflect their divergent roles.
Journal ArticleDOI
Putting genetic interactions in context through a global modular decomposition
Jeremy Bellay,Gowtham Atluri,Tina L. Sing,Kiana Toufighi,Michael Costanzo,Philippe Souza Moraes Ribeiro,Gaurav Pandey,Joshua A. Baller,Benjamin VanderSluis,Magali Michaut,Sangjo Han,Philip M. Kim,Grant W. Brown,Brenda J. Andrews,Charles Boone,Vipin Kumar,Chad L. Myers +16 more
TL;DR: A data mining approach was developed to exhaustively discover all block structures within Saccharomyces cerevisiae's genetic interaction network, which allowed for its complete modular decomposition and revealed the importance of the context of individual genetic interactions in their interpretation and revealed distinct trends among genetic interaction hubs.