Sondra Bahr

TL;DR: A network based on genetic interaction profiles reveals a functional map of the cell in which genes of similar biological processes cluster together in coherent subsets, and highly correlated profiles delineate specific pathways to define gene function.

TL;DR: A global genetic interaction network highlights the functional organization of a cell and provides a resource for predicting gene and pathway function and how coherent sets of negative or positive genetic interactions connect protein complex and pathways to map a functional wiring diagram of the cell.

TL;DR: This mutant collection should facilitate a wide range of systematic studies aimed at understanding the functions of essential genes, including roles for cohesin and condensin genes in spindle disassembly.

TL;DR: This work constructed a genome-wide set of targeted deletion alleles and introduced them into a filamentous S. cerevisiae strain and identified genes involved in morphologically distinct forms of filamentation: haploid invasive growth, biofilm formation, and diploid pseudohyphal growth.

TL;DR: Roles for the SUMO system are identified in the function of the AAA ATPase Cdc48p, the regulation of lipid metabolism, localization of the ATP-dependent endonuclease Dna2p, and recovery from the DNA-damage checkpoint.