J
Jin-Qiu Zhou
Researcher at ShanghaiTech University
Publications - 60
Citations - 3034
Jin-Qiu Zhou is an academic researcher from ShanghaiTech University. The author has contributed to research in topics: Telomere & Telomerase. The author has an hindex of 28, co-authored 56 publications receiving 2734 citations. Previous affiliations of Jin-Qiu Zhou include Laboratory of Molecular Biology & University of Miami.
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Journal ArticleDOI
Saccharomyces Rrm3p, a 5' to 3' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA.
TL;DR: In wild-type Saccharomyces cerevisiae, replication forks slowed during their passage through telomeric C(1-3)A/TG(3) tracts, greatly exacerbated in the absence of RRM3, shown here to encode a 5' to 3' DNA helicase.
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The Saccharomyces Pif1p DNA Helicase and the Highly Related Rrm3p Have Opposite Effects on Replication Fork Progression in Ribosomal DNA
TL;DR: A model in which replication fork pausing causes breakage and recombination in the rDNA is supported, as the Pif1p helicase and the highly related Rrm3p were rDNA associated in vivo.
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Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Chuanbing Bian,Chuanbing Bian,Chao Xu,Jianbin Ruan,Kenneth K. Lee,Tara L. Burke,Wolfram Tempel,Dalia Barsyte,Jing Li,Minhao Wu,Bo O. Zhou,Brian Fleharty,Ariel Paulson,Abdellah Allali-Hassani,Jin-Qiu Zhou,Georges Mer,Patrick A. Grant,Jerry L. Workman,Jianye Zang,Jinrong Min,Jinrong Min +20 more
TL;DR: In vitro and in vivo functional assays show that Sgf29 recognizes methylated H3K4 to recruit the SAGA complex to its targets sites and mediates histone H3 acetylation, underscoring the importance of Sf29 in gene regulation.
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Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
TL;DR: It is shown that Pif1p acts by inhibiting telomerase rather than telomere-telomere recombination, and this inhibition requires the helicase activity of PIF1p, which is a catalytic inhibitor of telomer enzyme-mediated telomeres lengthening.
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Creating a functional single-chromosome yeast
Yangyang Shao,Ning Lu,Zhenfang Wu,Chen Cai,Chen Cai,Shanshan Wang,Ling-Li Zhang,Ling-Li Zhang,Fan Zhou,Shijun Xiao,Lin Liu,Xiaofei Zeng,Huajun Zheng,Chen Yang,Zhihu Zhao,Guoping Zhao,Jin-Qiu Zhou,Xiaoli Xue,Zhongjun Qin +18 more
TL;DR: A functional single-chromosome yeast from a Saccharomyces cerevisiae haploid cell containing sixteen linear chromosomes is created by successive end-to-end chromosome fusions and centromere deletions to demonstrate an approach to exploration of eukaryote evolution with respect to chromosome structure and function.