J
John C. Chambers
Researcher at Imperial College London
Publications - 2
Citations - 832
John C. Chambers is an academic researcher from Imperial College London. The author has contributed to research in topics: Genome-wide association study & Homocysteine. The author has an hindex of 2, co-authored 2 publications receiving 761 citations. Previous affiliations of John C. Chambers include University of London.
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A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
John F. Peden,Jemma C. Hopewell,Danish Saleheen,John C. Chambers,Jorg Hager,Nicole Soranzo,Rory Collins,John Danesh,Paul Elliott,Martin Farrall,Kathy Stirrups,Weihua Zhang,Anders Hamsten,Anders Hamsten,Sarah Parish,Mark Lathrop,Hugh Watkins,Robert Clarke,Panos Deloukas,Jaspal S. Kooner,Anuj Goel,Halit Ongen,Rona J. Strawbridge,Rona J. Strawbridge,Simon Heath,Anders Mälarstig,Anders Mälarstig,Anna Helgadottir,John Öhrvik,John Öhrvik,Muhammed Murtaza,Simon C. Potter,Sarah E. Hunt,Marc Delepine,Shapour Jalilzadeh,Tomas Axelsson,Ann-Christine Syvänen,Rhian Gwilliam,Suzannah Bumpstead,Emma Gray,Sarah Edkins,Lasse Folkersen,Lasse Folkersen,Theodosios Kyriakou,Anders Franco-Cereceda,Anders Gabrielsen,Udo Seedorf,Per Eriksson,Per Eriksson,Alison Offer,Louise Bowman,Peter Sleight,Jane Armitage,Richard Peto,Gonçalo R. Abecasis,Nabeel Ahmed,Mark J. Caulfield,Peter Donnelly,Philippe Froguel,Angad S. Kooner,Mark I. McCarthy,Nilesh J. Samani,James Scott,Joban Sehmi,Angela Silveira,Angela Silveira,Mai-Lis Hellénius,Ferdinand M. van't Hooft,Ferdinand M. van't Hooft,Gunnar O Olsson,Stephan Rust,Gerd Assmann,Simona Barlera,Gianni Tognoni,Maria Grazia Franzosi,Pamela Linksted,Fiona Green,Asif Rasheed,Moazzam Zaidi,Nabi Shah,Maria Samuel,Nadeem Hayat Mallick,Muhammad Azhar,Khan Shah Zaman,Abdus Samad,M. Ishaq,Ali Raza Gardezi,Fazal-ur-Rehman Memon,Philippe M. Frossard,Tim D. Spector,Leena Peltonen,Leena Peltonen,Markku S. Nieminen,Juha Sinisalo,Veikko Salomaa,Samuli Ripatti,Derrick A Bennett,Karin Leander,Bruna Gigante,Ulf de Faire,Silvia Pietri,Francesca Gori,Roberto Marchioli,Suthesh Sivapalaratnam,John J.P. Kastelein,Mieke D. Trip,Eirini V. Theodoraki,George V. Dedoussis,Engert Jc,Salim Yusuf,Sonia S. Anand +110 more
TL;DR: Genome-wide association studies have identified 11 common variants convincingly associated with coronary artery disease (CAD), a modest number considering the apparent heritability of CAD(8) as mentioned in this paper.
Journal ArticleDOI
Homocysteine and Coronary Heart Disease: Meta- analysis of MTHFR Case-Control Studies, Avoiding Publication Bias
Robert Clarke,Derrick A Bennett,Sarah Parish,Petra Verhoef,Mariska Dötsch-Klerk,Mark Lathrop,Peng Xu,Børge G. Nordestgaard,Hilma Holm,Jemma C. Hopewell,Danish Saleheen,Toshihiro Tanaka,Sonia S. Anand,John C. Chambers,Marcus E. Kleber,Willem H. Ouwehand,Yoshiji Yamada,Clara C. Elbers,Bas J M Peters,Alexandre F.R. Stewart,Muredach M. Reilly,Barbara Thorand,Salim Yusuf,James C. Engert,Themistocles L. Assimes,Jaspal S. Kooner,John Danesh,Hugh Watkins,Nilesh J. Samani,Rory Collins,Richard Peto +30 more
TL;DR: A meta-analysis of unpublished datasets suggests that an increase in homocysteine levels is not likely to result in a increase in risk of coronary heart disease.