J
John H. Cardellina
Researcher at Montana State University
Publications - 155
Citations - 7979
John H. Cardellina is an academic researcher from Montana State University. The author has contributed to research in topics: Calanolide A & Cell killing. The author has an hindex of 48, co-authored 154 publications receiving 7576 citations. Previous affiliations of John H. Cardellina include University of Illinois at Urbana–Champaign & United States Department of Commerce.
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The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.
Yoel Kashman,Kirk R. Gustafson,Richard W. Fuller,John H. Cardellina,James B. McMahon,Michael J. Currens,Robert W. Buckheit,Stephen H. Hughes,Gordon M. Cragg,Michael R. Boyd +9 more
TL;DR: Calanolide A was active not only against the AZT-resistant G-9106 strain of HIV-1 but also against the pyridinone-resistant A17 strain, which was of particular interest since the A17 virus is highly resistant to previously known HIV- 1 specific, non-nucleoside RT inhibitors.
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Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity
Dehe Kong,Eun-Jung Park,Andrew G. Stephen,Maura Calvani,John H. Cardellina,Anne Monks,Robert J. Fisher,Robert H. Shoemaker,Giovanni Melillo +8 more
TL;DR: It is shown that it is possible to identify small molecules that inhibit HIF-1 DNA binding to endogenous promoters and echinomycin, a small-molecule known to bind DNA in a sequence-specific fashion, was investigated.
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Ulosantoin, a potent insecticide from the sponge Ulosa ruetzleri
Bradford C. Vanwagenen,Raymond D. Larsen,John H. Cardellina,David Randazzo,Zev Lidert,Colin Swithenbank +5 more
TL;DR: A phosphorylated hydantoin has been isolated from organic soluble extracts of the sponge Ulosa ruetzleri and found to exhibit marked insecticidal activity against tobacco hornworm larvae and cockroaches.
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AIDS-Antiviral Sulfolipids From Cyanobacteria (Blue-Green Algae)
Kirk R. Gustafson,John H. Cardellina,Richard W. Fuller,Owen S. Weislow,Rebecca Kiser,Kenneth M. Snader,Gregory M. L. Patterson,Michael R. Boyd +7 more
TL;DR: A new class of HIV-1-inhibitory compounds, the sulfonic acid-containing glycolipids, was discovered through the use of the microculture assay to guide the fractionation and purification process.
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Circulins A and B. Novel human immunodeficiency virus (HIV)-inhibitory macrocyclic peptides from the tropical tree Chassalia parvifolia.
Kirk R. Gustafson,Raymond C. Sowder,Louis E. Henderson,Ian Parsons,Yoel Kashman,John H. Cardellina,James B. McMahon,Robert W. Buckheit,Lewis K. Pannell,Michael R. Boyd +9 more