J
Joseph C. Corbo
Researcher at Washington University in St. Louis
Publications - 94
Citations - 8604
Joseph C. Corbo is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Enhancer & Gene. The author has an hindex of 38, co-authored 91 publications receiving 7676 citations. Previous affiliations of Joseph C. Corbo include Brigham and Women's Hospital & Stanford University.
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Journal ArticleDOI
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
Amy E. Pasquinelli,Brenda J. Reinhart,Frank J. Slack,Mark Q. Martindale,Mitzi I. Kuroda,Betsy Maller,David C. Hayward,Eldon E. Ball,Bernard M. Degnan,Peter Müller,Jürg Spring,Ashok Srinivasan,Mark C. Fishman,John R. Finnerty,Joseph C. Corbo,Michael P. Levine,Patrick S. Leahy,Eric H. Davidson,Gary Ruvkun +18 more
TL;DR: Two small RNAs regulate the timing of Caenorhabditis elegans development and may control late temporal transitions during development across animal phylogeny.
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Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis
TL;DR: Evidence is presented that the embryo of the ascidian, Ciona intestinalis, is an easily manipulated system for investigating the establishment of basic chordate tissues and organs, thereby raising the possibility that the Notch signaling pathway plays a role in notochord differentiation.
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Doublecortin is required in mice for lamination of the hippocampus but not the neocortex.
Joseph C. Corbo,Joseph C. Corbo,Thomas A.S Deuel,Jeffrey M. Long,Patricia LaPorte,Elena Tsai,Anthony Wynshaw-Boris,Christopher A. Walsh +7 more
TL;DR: Behavioral tests show defects in context and cued conditioned fear tests, suggesting that deficits in hippocampal learning accompany the abnormal cytoarchitecture.
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β-Glucuronidase (GUS) transposons for ecological and genetic studies of rhizobia and other Gram-negative bacteria
Kate J. Wilson,Angela Sessitsch,Joseph C. Corbo,Ken E. Giller,Antoon D. L. Akkermans,Richard A. Jefferson +5 more
TL;DR: A series of transposons are described which contain the gusA gene, encoding β-glucuronidase (GUS), expressed from a variety of promoters, both regulated and constitutive, which constitute powerful new tools for studying the ecology and population biology of bacteria in the environment and in association with plants.
Journal ArticleDOI
Genetic Interactions between Doublecortin and Doublecortin-like Kinase in Neuronal Migration and Axon Outgrowth
Thomas A.S. Deuel,Judy S. Liu,Joseph C. Corbo,Seung-Yun Yoo,Lucy B. Rorke-Adams,Christopher A. Walsh +5 more
TL;DR: It is shown that mice mutant for both Dcx and Dclk demonstrate perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization, a process critical to both neuronal migration and axon outgrowth.