Joseph Loscalzo

TL;DR: The active component in deerfly salivary gland extract appears to be a protein that is comparatively more potent than the disintegrins present in viper venoms, and isolation and characterization of this protein may provide different directions in therapeutics and studies of normal platelet physiology.

TL;DR: The data suggest that the effects of thrombolytic agents on platelet function are complex and can be modulated by antiplatelet prostaglandins.

TL;DR: Analysis of molecular and cellular mechanisms of adaptation in response to the pervasive challenge of obesity, a chronic condition resulting from sustained nutrient excess that prompts chaotic exploration for system stability associated with tradeoffs and a risk of adverse outcomes, holds the promise of gaining novel insights into physiological adaptation in health and disease.

TL;DR: Common COMT polymorphisms were associated with incident CVD, and this association was modified by randomized allocation to aspirin or vitamin E.

TL;DR: Temporal bias acts to undermine the validity of predictions by over-emphasizing features close to the outcome of interest as discussed by the authors, leading to exaggerated effect sizes, false negative predictions, and replication failure.