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Joseph Loscalzo

Researcher at Brigham and Women's Hospital

Publications -  875
Citations -  79338

Joseph Loscalzo is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Nitric oxide & Platelet. The author has an hindex of 129, co-authored 828 publications receiving 71573 citations. Previous affiliations of Joseph Loscalzo include Veterans Health Administration & University of California, Los Angeles.

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Antioxidant enzyme deficiencies and vascular disease.

TL;DR: This article considers three distinct antioxidant enzyme deficiencies – glucose-6-phosphate dehydrogenase, glutathione peroxidase-1 and glutathienase-3 – and their consequences for vascular disease.
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Association Between Circulating CD4+ T Cell Methylation Signatures of Network-Oriented SOCS3 Gene and Hemodynamics in Patients Suffering Pulmonary Arterial Hypertension

TL;DR: In this article , a network-oriented study which integrates circulating CD4+ T cell DNA methylation signatures, hemodynamic parameters, and validation experiments in PAH patients at first diagnosis or early follow-up was conducted.
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Reciprocating autocatalytic interactions between platelets and the activation system

TL;DR: Observations imply that PGN activation may be an autocatalytic process on the platelet surface and provide evidence for a unique reciprocating mechanism governing the interaction between platelets and the plasminogen activation system.
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Maintenance of certification: Good intentions gone awry.

TL;DR: In the efforts to be responsive to a society that demands ever more demonstrable evidence of the authors' continued competence as practitioners, certifying bodies—in the case of internal medicine and cardiovascular medicine, the American Board of Internal Medicine—embarked on two initiatives in the past 25 years.
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Recent Advances in Systems and Network Medicine: Meeting Report from the First International Conference in Systems and Network Medicine.

Emma Kurnat-Thoma, +42 more
TL;DR: The First International Conference in Systems and Network Medicine gathered together 200 global thought leaders, scientists, clinicians, academicians, industry and government experts, medical and graduate students, postdoctoral scholars and policymakers and fostered formation of new insights and possibilities for health care systems advances.