J
Josine E. Verhoeven
Researcher at VU University Medical Center
Publications - 37
Citations - 2269
Josine E. Verhoeven is an academic researcher from VU University Medical Center. The author has contributed to research in topics: Anxiety & Major depressive disorder. The author has an hindex of 22, co-authored 34 publications receiving 1712 citations. Previous affiliations of Josine E. Verhoeven include University of California, San Francisco & VU University Amsterdam.
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Journal ArticleDOI
Oxidative stress, inflammation and treatment response in major depression
Daniel Lindqvist,Daniel Lindqvist,Firdaus S. Dhabhar,S. Jill James,Christina M. Hough,Felipe A. Jain,F. Saverio Bersani,F. Saverio Bersani,Victor I. Reus,Josine E. Verhoeven,Josine E. Verhoeven,Elissa S. Epel,Laura Mahan,Rebecca Rosser,Owen M. Wolkowitz,Synthia H. Mellon +15 more
TL;DR: Investigating markers of inflammation and oxidative stress in unmedicated MDD subjects and controls found poorer antidepressant treatment response was related to higher baseline levels of the major oxidative stress marker, F2-isoprostanes, in vivo, and antidepressant response was associated with changes in oxidative (8-OHdG) and inflammatory (IL-6) markers.
Journal ArticleDOI
Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging.
Daniel Lindqvist,Elissa S. Epel,Synthia H. Mellon,Brenda W.J.H. Penninx,Dóra Révész,Josine E. Verhoeven,Victor I. Reus,Jue Lin,Laura Mahan,Christina M. Hough,Rebecca Rosser,F. Saverio Bersani,Elizabeth H. Blackburn,Owen M. Wolkowitz +13 more
TL;DR: A deeper understanding of cellular aging in psychiatric illnesses could lead to re-conceptualizing them as systemic illnesses with manifestations inside and outside the brain and could identify new treatment targets.
Journal ArticleDOI
Major depressive disorder and accelerated cellular aging: results from a large psychiatric cohort study
Josine E. Verhoeven,Dóra Révész,Elissa S. Epel,Jue Lin,Owen M. Wolkowitz,Brenda W.J.H. Penninx +5 more
TL;DR: It is demonstrated that depressed patients show accelerated cellular aging according to a ‘dose–response’ gradient: those with the most severe and chronic MDD showed the shortest TL.
Journal ArticleDOI
The Association Between Psychiatric Disorders and Telomere Length: A Meta-Analysis Involving 14,827 Persons.
Sabrina M. Darrow,Josine E. Verhoeven,Dóra Révész,Daniel Lindqvist,Brenda W.J.H. Penninx,Kevin L. Delucchi,Owen M. Wolkowitz,Carol A. Mathews +7 more
TL;DR: A robust effect size of LTL shortening was observed for psychiatric disorders as a whole compared with controls and the heterogeneity between studies could not be explained by a model that included these variables as well as sex and assay method.
Journal ArticleDOI
Body mass index is negatively associated with telomere length : a collaborative cross-sectional meta-analysis of 87 observational studies
Marij Gielen,Geja J. Hageman,Evangelia Antoniou,Katarina Nordfjäll,Massimo Mangino,Muthuswamy Balasubramanyam,Tim De Meyer,Audrey E. Hendricks,Audrey E. Hendricks,Erik J. Giltay,Steven C. Hunt,Jennifer A. Nettleton,Klelia D. Salpea,Vanessa A. Diaz,Ramin Farzaneh-Far,Gil Atzmon,Sarah E. Harris,Lifang Hou,David Gilley,Iiris Hovatta,Iiris Hovatta,Jeremy D. Kark,Hisham Nassar,David J. Kurz,Karen A. Mather,Peter Willeit,Yun-Ling Zheng,Sofia Pavanello,Ellen W. Demerath,Line Rode,Daniel Bunout,Andrew Steptoe,Lisa A. Boardman,Amelia Marti,Amelia Marti,Belinda L. Needham,Wei Zheng,Rosalind Ramsey-Goldman,Andrew J. Pellatt,Jaakko Kaprio,Jonathan N. Hofmann,Christian Gieger,Giuseppe Paolisso,Jacob B. H. Hjelmborg,Lisa Mirabello,Teresa E. Seeman,Jason Y.Y. Wong,Pim van der Harst,Linda Broer,Florian Kronenberg,Barbara Kollerits,Timo E. Strandberg,Daniel Eisenberg,Catherine Duggan,Josine E. Verhoeven,Roxanne Schaakxs,Raffaela Zannolli,Rosana Maria dos Reis,Fadi J. Charchar,Maciej Tomaszewski,Maciej Tomaszewski,Ute Mons,Ilja Demuth,Andrea Elena Iglesias Molli,Guo Cheng,Dmytro Krasnienkov,Bianca D’Antono,Marek Kasielski,Barry J. McDonnell,Richard P. Ebstein,Kristina Sundquist,Guillaume Paré,Michael Chong,Maurice P. Zeegers +73 more
TL;DR: In this paper, a collaborative cross-sectional meta-analysis of observational studies was conducted to investigate the associations between BMI and leukocyte telomere length across the life span.