K
Kasper Harpsøe
Researcher at University of Copenhagen
Publications - 86
Citations - 3050
Kasper Harpsøe is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Light curve & Receptor. The author has an hindex of 28, co-authored 79 publications receiving 2575 citations. Previous affiliations of Kasper Harpsøe include Geological Museum.
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Journal ArticleDOI
GPCRdb in 2018: adding GPCR structure models and ligands.
Gáspár Pándy-Szekeres,Christian Munk,Tsonko M. Tsonkov,Stefan Mordalski,Kasper Harpsøe,Alexander S. Hauser,Andrzej J. Bojarski,David E. Gloriam +7 more
TL;DR: GPCRome-wide homology models of unprecedented quality are reported, and roughly 150 000 GPCR ligands with data on biological activities and commercial availability are provided, to enable scientific investigation for the wider G PCR community.
Journal ArticleDOI
A ring system detected around the centaur (10199) chariklo
Felipe Braga-Ribas,Bruno Sicardy,Jose Luis Ortiz,Colin Snodgrass,F. Roques,R. Vieira-Martins,R. Vieira-Martins,R. Vieira-Martins,Julio Camargo,Marcelo Assafin,Rene Duffard,Emmanuel Jehin,Joe Pollock,Rodrigo Leiva,Marcelo Emilio,D. I. Machado,C. Colazo,E. Lellouch,Jesper Skottfelt,Jesper Skottfelt,Michaël Gillon,N. Ligier,L. Maquet,G. Benedetti-Rossi,A. Ramos Gomes,Pierre Kervella,Hektor Monteiro,Rafael Sfair,M. El Moutamid,M. El Moutamid,Gonzalo Tancredi,J. Spagnotto,Alain Maury,Nicolás Morales,Ricardo Gil-Hutton,S. Roland,A. Ceretta,Shenghong Gu,Xuefeng Wang,Kasper Harpsøe,Kasper Harpsøe,Markus Rabus,Markus Rabus,Jean Manfroid,Cyrielle Opitom,L. Vanzi,L. Mehret,L. Lorenzini,E. M. Schneiter,R. Melia,J. Lecacheux,François Colas,Frédéric Vachier,Thomas Widemann,L. Almenares,R. G. Sandness,F. Char,V. Perez,P. Lemos,Nicolás Marín Martínez,U. G. Jørgensen,U. G. Jørgensen,Martin Dominik,Fernando Roig,Daniel E. Reichart,Aaron P. LaCluyze,J. B. Haislip,K. M. Ivarsen,J. P. Moore,N. R. Frank,D. G. Lambas,D. G. Lambas +71 more
TL;DR: Observations of a multichord stellar occultation revealed the presence of a ring system around (10199) Chariklo, which is a Centaur—that is, one of a class of small objects orbiting primarily between Jupiter and Neptune—with an equivalent radius of 124 9 kilometres.
Journal ArticleDOI
High-precision photometry by telescope defocussing. I. The transiting planetary system WASP-5
John Southworth,Tobias C. Hinse,U. G. Joergensen,Martin Dominik,Davide Ricci,Martin Burgdorf,Allan Hornstrup,P. J. Wheatley,Timo Anguita,V. Bozza,S. Calchi Novati,Kasper Harpsøe,Per Kjaergaard,C. Liebig,Luigi Mancini,G. Masi,M. Mathiasen,S. Rahvar,Gaetano Scarpetta,Colin Snodgrass,Jean Surdej,Christina C. Thöne,M. Zub +22 more
TL;DR: In this article, high-precision photometry of three transits of the extrasolar planetary system WASP-2, obtained by defocussing the telescope, and achieving point-to-point scatters of between 0.42 and 0.73 mmag.
Journal ArticleDOI
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.
Yao Peng,Yao Peng,Yao Peng,John D. McCorvy,Kasper Harpsøe,Katherine Lansu,Shuguang Yuan,Petr Popov,Petr Popov,Lu Qu,Lu Qu,Mengchen Pu,Tao Che,Louise F. Nikolajsen,Louise F. Nikolajsen,Xi Ping Huang,Yiran Wu,Ling Shen,Walden E. Bjørn-Yoshimoto,Kang Ding,Daniel Wacker,Gye Won Han,Jianjun Cheng,Vsevolod Katritch,Vsevolod Katritch,Anders A. Jensen,Michael A. Hanson,Suwen Zhao,David E. Gloriam,Bryan L. Roth,Raymond C. Stevens,Raymond C. Stevens,Zhi-Jie Liu +32 more
TL;DR: This study investigates the structural basis of polypharmacology at canonical GPCRs and illustrates how understanding characteristic patterns of ligand-receptor interaction and activation may ultimately facilitate drug design at multiple GPCR.
Journal ArticleDOI
GPCRdb: the G protein-coupled receptor database – an introduction
Christian Munk,Vignir Isberg,Stefan Mordalski,Kasper Harpsøe,Krzysztof Rataj,Alexander S. Hauser,Peter Kolb,Andrzej J. Bojarski,Gert Vriend,David E. Gloriam +9 more
TL;DR: This review is intended to introduce new users to the services in GPCRdb, which meets three overall purposes: to provide reference data in an integrated, annotated and structured fashion, with a focus on sequences, structures, single‐point mutations and ligand interactions, and to equip the community with a suite of web tools for swift analysis of structures, sequence similarities, receptor relationships, and ligands target profiles.