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Keith F. Tipton
Researcher at Trinity College, Dublin
Publications - 289
Citations - 12298
Keith F. Tipton is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Monoamine oxidase & Amine oxidase. The author has an hindex of 50, co-authored 288 publications receiving 11561 citations. Previous affiliations of Keith F. Tipton include University of Florence.
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Journal ArticleDOI
The therapeutic potential of monoamine oxidase inhibitors.
TL;DR: This work evaluates claims and some counter-claims made about the physiological importance of these enzymes and the potential of their inhibitors in the light of what the authors know, and still have to learn, of the structure, function and genetics of the monoamine oxidases and the disparate actions of their inhibitor.
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The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.
Peter I. Mackenzie,Ida S. Owens,Brian Burchell,Karl Walter Bock,Amos Marc Bairoch,Alain Bélanger,Sylvie Fournel-Gigleux,Mitchell D. Green,Dean W. Hum,Takashi Iyanagi,Doron Lancet,Pierre Louisot,Jacques Magdalou,Jayanla Roy Chowdhury,Joseph K. Ritter,Harry Schachter,Thomas R. Tephly,Keith F. Tipton,Daniel W. Nebert +18 more
TL;DR: This review represents an update of the nomenclature system for the UDP glucuronosyltransferase gene superfamily, which is based on divergent evolution and is anticipated that this UGT gene nomenClature system will require updating on a regular basis.
Journal ArticleDOI
Advances in Our Understanding of the Mechanisms of the Neurotoxicity of MPTP and Related Compounds
Keith F. Tipton,Thomas P. Singer +1 more
TL;DR: The present account will concentrate on more recent discoveries concerning the mechanism by which MPTP exerts its selective neurotoxic effects and the unresolved problems that remain.
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Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project
Chris F. Taylor,Chris F. Taylor,Dawn Field,Susanna-Assunta Sansone,Susanna-Assunta Sansone,Jan Aerts,Rolf Apweiler,Michael Ashburner,Catherine A. Ball,Pierre-Alain Binz,Molly Bogue,Timothy F. Booth,Alvis Brazma,Ryan R. Brinkman,Adam Clark,Eric W. Deutsch,Oliver Fiehn,Jennifer Fostel,Peter Ghazal,Frank Gibson,Tanya Gray,Graeme R. Grimes,John M. Hancock,Nigel Hardy,Henning Hermjakob,Randall K. Julian,Matthew D. Kane,Carsten Kettner,Christopher R. Kinsinger,Eugene Kolker,Martin Kuiper,Nicolas Le Novère,Jim Leebens-Mack,Suzanna E. Lewis,Phillip Lord,Ann-Marie Mallon,Nishanth Marthandan,Hiroshi Masuya,Ruth McNally,Alexander Mehrle,Norman Morrison,Sandra Orchard,John Quackenbush,James M. Reecy,Donald G. Robertson,Philippe Rocca-Serra,Henry Rodriguez,Heiko Rosenfelder,Javier Santoyo-Lopez,Richard H. Scheuermann,Daniel Schober,Barry Smith,Jason Snape,Christian J. Stoeckert,Keith F. Tipton,Peter Sterk,Andreas Untergasser,Jo Vandesompele,Stefan Wiemann +58 more
TL;DR: The Minimum Information for Biological and Biomedical Investigations (MIBBI) project aims to foster the coordinated development of minimum-information checklists and provide a resource for those exploring the range of extant checklists.
Journal ArticleDOI
Monoamine oxidase A and B: a useful concept?
TL;DR: The usefulness of the concept of the existence of two functionally distinct forms of the enzyme is assessed, without exploring the possible nature of any such forms.