K
Kendall N. Houk
Researcher at University of California, Los Angeles
Publications - 1025
Citations - 62686
Kendall N. Houk is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Catalysis & Cycloaddition. The author has an hindex of 112, co-authored 997 publications receiving 54877 citations. Previous affiliations of Kendall N. Houk include Texas A&M University & University of Notre Dame.
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Die Bindungslokalisierungsenergien der aromatischen Bismethano[14]annulene
Maja Nendel,Kendall N. Houk,L. M. Tolbert,Emanuel Vogel,Haijun Jiao,Paul von Ragué Schleyer,Paul von Ragué Schleyer +6 more
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Theory and Modeling of Stereoselective Organic Reactions
Kendall N. Houk,M. N. Paddon-Row,Nelson G. Rondan,Yun-Dong Wu,Frank K. Brown,David C. Spellmeyer,James T. Metz,Y. Li and,Richard J. Loncharich +8 more
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Selective skeletal editing of polycyclic arenes using organophotoredox dearomative functionalization
TL;DR: In this article , a general organophotoredox approach for the chemo-and regioselective dearomatization of structurally diverse polycyclic aromatics is described.
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Computations Reveal That Electron-Withdrawing Leaving Groups Facilitate Intramolecular Conjugate Displacement Reactions by Negative Hyperconjugation.
TL;DR: Quantum mechanical investigations with density functional theory show that ICDs involve a stepwise addition, forming an intermediate stabilized carbanion, followed by elimination.
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Development of indazole mineralocorticoid receptor antagonists and investigation into their selective late-stage functionalization.
Kun Liu,Ravi Kurukulasuriya,Kevin D. Dykstra,Lisa DiMichelle,Jinchu Liu,Petr Vachal,Anthony Ogawa,Robert J. DeVita,Dong-Ming Shen,Qiang Tan,Yili Chen,Don Gauthier,Andreas Verras,Alejandro Crespo,Beata Zamlynny,Jeffrey Madwed,Maarten Hoek,Thomas Bateman,Yun-Fang Yang,Kendall N. Houk,Shane W. Krska,Tim Cernak +21 more
TL;DR: A case study in late-stage functionalization towards the development of a new class of indazole-based mineralocorticoid receptor antagonists (MRA) with excellent metabolic stability through the use of modern CH borylation chemistry.