K
Kendall N. Houk
Researcher at University of California, Los Angeles
Publications - 1025
Citations - 62686
Kendall N. Houk is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Catalysis & Cycloaddition. The author has an hindex of 112, co-authored 997 publications receiving 54877 citations. Previous affiliations of Kendall N. Houk include Texas A&M University & University of Notre Dame.
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Lewis acid catalysis alters the shapes and products of bis-pericyclic Diels-Alder transition states.
TL;DR: The reactions of cyclopentadiene with α-keto-β,γ-unsaturated phosphonates or with nitroalkenes proceed through an unsymmetrical bis-pericyclic transition state to give both Diels−Alder and hetero-Diels+Alder cycloadducts.
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Cycloadditions of cyclohexynes and cyclopentyne.
TL;DR: The strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds and the observed regioselectivities are explained by the distortion/interaction model.
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Non-directed allylic C–H acetoxylation in the presence of Lewis basic heterocycles
Hasnain A. Malik,Buck L. H. Taylor,John Ryan Kerrigan,Jonathan E. Grob,Kendall N. Houk,J. Du Bois,Lawrence G. Hamann,Andrew Patterson +7 more
TL;DR: Two approaches are pursued in parallel that allow product conversion in this representative system: Lewis acids are found to be effective in situ blocking groups for the Lewis basic site, and a pre-formed pyridine N-oxide is shown to enable high yield of allylic C-H acetoxylation.
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Rh-Catalyzed (5+2) Cycloadditions of 3-Acyloxy-1,4-enynes and Alkynes: Computational Study of Mechanism, Reactivity, and Regioselectivity
TL;DR: The mechanism of Rh-catalyzed (5+2) cycloadditions of 3-acyloxy-1,4-enyne and alkynes is investigated using density functional theory calculations and the 1,2-ACYloxy migration is found to be the rate-determining step of the catalytic cycle.
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Mechanisms of peroxynitrous acid and methyl peroxynitrite, ROONO (R = H, Me), rearrangements: A conformation-dependent homolytic dissociation
TL;DR: In this article, the OONO dihedral angle has a remarkably large influence on the barriers for cleavage of the O−O bonds, which influences the subsequent radical recombination to yield nitrates (RONO2).