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Yang Shi

Researcher at Boston Children's Hospital

Publications -  327
Citations -  52031

Yang Shi is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Transcription factor & Histone. The author has an hindex of 102, co-authored 309 publications receiving 46316 citations. Previous affiliations of Yang Shi include Portland State University & University of Kentucky.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
PatentDOI

Histone demethylation mediated by the nuclear amine oxidase homolog lsd1

Yang Shi, +1 more
- 16 Dec 2005 - 
TL;DR: In this paper, the authors identify a histone demethylase conserved from S. pombe to human and reveal dynamic regulation of histone methylation by both histonemethylases and demethylases.
Journal ArticleDOI

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

Miao-Chih Tsai, +8 more
- 06 Aug 2010 - 
TL;DR: The results suggest that lincRNAs may serve as scaffolds by providing binding surfaces to assemble select histone modification enzymes, thereby specifying the pattern of histone modifications on target genes.
Journal ArticleDOI

Histone methylation: a dynamic mark in health, disease and inheritance

Eric L. Greer, +1 more
- 03 Apr 2012 - 
TL;DR: This work provides a broad overview of how histone methylation is regulated and leads to biological outcomes and suggests its links to disease and ageing and possibly to transmission of traits across generations are illustrated.
Journal ArticleDOI

A DNA Vector-Based RNAi Technology to Suppress Gene Expression in Mammalian Cells

Guangchao Sui, +5 more
- 16 Apr 2002 - 
TL;DR: This work reports a technology that allows synthesis of small interfering RNAs from DNA templates in vivo to efficiently inhibit endogenous gene expression and demonstrates robust inhibition of several endogenous genes of diverse functions in mammalian cells.