K
Kiyoko Iwatsuki-Horimoto
Researcher at University of Tokyo
Publications - 111
Citations - 7279
Kiyoko Iwatsuki-Horimoto is an academic researcher from University of Tokyo. The author has contributed to research in topics: Virus & Medicine. The author has an hindex of 32, co-authored 79 publications receiving 4640 citations.
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Journal ArticleDOI
A replication-incompetent influenza virus bearing the HN glycoprotein of human parainfluenza virus as a bivalent vaccine.
Hirofumi Kobayashi,Kiyoko Iwatsuki-Horimoto,Maki Kiso,Ryuta Uraki,Yurie Ichiko,Toru Takimoto,Yoshihiro Kawaoka +6 more
TL;DR: Results indicate that PB2-KO virus expressing the HN of HPIV3 has the potential to be a novel bivalent vaccine against influenza and human parainfluenza viruses.
Journal ArticleDOI
Emergence of Oseltamivir-Resistant H7N9 Influenza Viruses in Immunosuppressed Cynomolgus Macaques.
Maki Kiso,Kiyoko Iwatsuki-Horimoto,Seiya Yamayoshi,Ryuta Uraki,Mutsumi Ito,Noriko Nakajima,Shinya Yamada,Masaki Imai,Eiryo Kawakami,Yuriko Tomita,Satoshi Fukuyama,Yasushi Itoh,Kazumasa Ogasawara,Tiago J. S. Lopes,Tiago J. S. Lopes,Tokiko Watanabe,Louise H. Moncla,Hideki Hasegawa,Thomas C. Friedrich,Gabriele Neumann,Yoshihiro Kawaoka,Yoshihiro Kawaoka +21 more
TL;DR: Oseltamivir treatment at 2 different doses reduced A(H7N9) viral titers in infected animals, but even high-dose oseltAMivir did not block viral replication sufficiently to suppress the emergence of resistant variants.
Journal ArticleDOI
The Microminipig as an Animal Model for Influenza A Virus Infection
Kiyoko Iwatsuki-Horimoto,Noriko Nakajima,Masatoshi Shibata,Kenta Takahashi,Yuko Sato,Maki Kiso,Seiya Yamayoshi,Mutsumi Ito,Satoko Enya,Masayoshi Otake,Akihisa Kangawa,Tiago J. S. Lopes,Hirotaka Ito,Hideki Hasegawa,Yoshihiro Kawaoka,Yoshihiro Kawaoka +15 more
TL;DR: The distribution of influenza virus receptors in the respiratory tract of the microminipig was similar to that of the pig, and the sensitivity of micromInipigs to influenza A viruses was the same as that of miniature pigs, suggesting that microm inipigs represent a novel animal model for influenza A virus infection.
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Identification of the porcine cytomegalovirus major capsid protein gene.
TL;DR: A major capsid protein (MCP) gene homologue of porcine cytomegalovirus (PCMV) was identified and established polymerase chain reaction (PCR) protocols using primers corresponding to MCP gene sequences for detection of PCMV infection.
Journal ArticleDOI
Serological evidence of infection of dogs with human influenza viruses in Japan
Taisuke Horimoto,Fumihiro Gen,Shin Murakami,Kiyoko Iwatsuki-Horimoto,Kentaro Kato,Hiroomi Akashi,Masaharu Hisasue,Masahiro Sakaguchi,Yoshihiro Kawaoka,Ken Maeda +9 more
TL;DR: Recent infections of racing and pet dogs with H3N8 virus of equine origin in the USA after 2004 and retrospectively in the UK in 2002, as well as with highly pathogenic H5N1 avian virus in Thailand in 2004, revealed that dogs are susceptible to influenza A viruses.