K
Klaus Seppi
Researcher at Innsbruck Medical University
Publications - 366
Citations - 25650
Klaus Seppi is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Parkinsonism & Medicine. The author has an hindex of 74, co-authored 317 publications receiving 20534 citations. Previous affiliations of Klaus Seppi include University of Innsbruck.
Papers
More filters
Journal ArticleDOI
Second consensus statement on the diagnosis of multiple system atrophy
Sid Gilman,Gregor K. Wenning,Phillip A. Low,David J. Brooks,C. J. Mathias,John Q. Trojanowski,Nicholas W. Wood,Carlo Colosimo,Alexandra Durr,Clare J. Fowler,Horacio Kaufmann,Thomas Klockgether,AJ Lees,Werner Poewe,Niall Quinn,Tamas Revesz,David Robertson,Paola Sandroni,Klaus Seppi,Marie Vidailhet +19 more
TL;DR: New criteria for diagnosis of multiple system atrophy have simplified the previous criteria, have incorporated current knowledge, and are expected to enhance future assessments of the disease.
Journal ArticleDOI
Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria
Günter U. Höglinger,Gesine Respondek,Maria Stamelou,Carolin Kurz,Keith A. Josephs,Anthony E. Lang,Brit Mollenhauer,Ulrich Müller,Christer Nilsson,Jennifer L. Whitwell,Thomas Arzberger,Elisabet Englund,Ellen Gelpi,Armin Giese,David J. Irwin,Wassilios G. Meissner,Wassilios G. Meissner,Alexander Pantelyat,Alex Rajput,John C. van Swieten,Claire Troakes,Angelo Antonini,Kailash P. Bhatia,Yvette Bordelon,Yaroslau Compta,Jean-Christophe Corvol,Carlo Colosimo,Dennis W. Dickson,Richard Dodel,Leslie W. Ferguson,Murray Grossman,Jan Kassubek,Florian Krismer,Johannes Levin,Stefan Lorenzl,Huw R. Morris,Peter J. Nestor,Wolfgang H. Oertel,Werner Poewe,Gil D. Rabinovici,James B. Rowe,Gerard D. Schellenberg,Klaus Seppi,Thilo van Eimeren,Gregor K. Wenning,Adam L. Boxer,Lawrence I. Golbe,Irene Litvan +47 more
TL;DR: Clinical diagnostic criteria, published in 1996 by the National Institute of Neurological Disorders and Stroke/Society for PSP have excellent specificity, but their sensitivity is limited for variant PSP syndromes with presentations other than Richardson's syndrome.
Journal ArticleDOI
The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson's disease
Klaus Seppi,Daniel Weintraub,Miguel Coelho,Santiago Perez-Lloret,Susan H. Fox,Regina Katzenschlager,Eva-Maria Hametner,Werner Poewe,Olivier Rascol,Christopher G. Goetz,Cristina Sampaio +10 more
TL;DR: The objective of this work was to update previous EBM reviews on treatments for PD with a focus on non‐motor symptoms and found that most of the other interventions there is insufficient evidence to make adequate conclusions on their efficacy.
Journal ArticleDOI
A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
Alexander Zimprich,Anna Benet-Pagès,Walter Struhal,Elisabeth Graf,Sebastian H. Eck,Marc N. Offman,Dietrich Haubenberger,Sabine Spielberger,Eva C. Schulte,Peter Lichtner,Shaila C. Rossle,Norman Klopp,Elisabeth Wolf,Klaus Seppi,Walter Pirker,Stefan Presslauer,Brit Mollenhauer,Regina Katzenschlager,Thomas Foki,Christoph Hotzy,Eva M. Reinthaler,Ashot S. Harutyunyan,Robert Kralovics,Annette Peters,Fritz Zimprich,Thomas Brücke,Werner Poewe,Eduard Auff,Claudia Trenkwalder,Burkhard Rost,Gerhard Ransmayr,Juliane Winkelmann,Thomas Meitinger,Tim M. Strom +33 more
TL;DR: An Austrian family with 16 affected individuals by exome sequencing found a missense mutation, c.1858G>A (p.Asp620Asn), in the VPS35 gene in all seven affected family members who are alive, and found the same variant cosegregating with the disease in an autosomal-dominant mode with high but incomplete penetrance.