K
Klaus Seppi
Researcher at Innsbruck Medical University
Publications - 366
Citations - 25650
Klaus Seppi is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Parkinsonism & Medicine. The author has an hindex of 74, co-authored 317 publications receiving 20534 citations. Previous affiliations of Klaus Seppi include University of Innsbruck.
Papers
More filters
Journal ArticleDOI
Differences in MDS‐UPDRS Scores Based on Hoehn and Yahr Stage and Disease Duration
Matej Skorvanek,Pablo Martinez-Martin,Norbert Kovács,Mayela Rodríguez-Violante,Jean-Christophe Corvol,Pille Taba,Klaus Seppi,Oleg Levin,Anette Schrag,Thomas Foltynie,Mario Alvarez-Sanchez,Tomoko Arakaki,Zsuzsanna Aschermann,Iciar Aviles-Olmos,Eve Benchetrit,Charline Benoit,Alberto Bergareche-Yarza,Amin Cervantes-Arriaga,Anabel Chade,Florence Cormier,Veronika Datieva,David A. Gallagher,Nelida Garretto,Zuzana Gdovinova,Oscar S. Gershanik,Milan Grofik,Vladimir Han,Jing Huang,Liis Kadastik-Eerme,Monica M. Kurtis,Graziella Mangone,Juan Carlos Martínez-Castrillo,Amelia Mendoza-Rodriguez,Michal Minár,Henry Moore,Mari Muldmaa,Christoph Mueller,Bernadette Pinter,Werner Poewe,Karin Rallmann,Eva Reiter,Carmen Rodriguez-Blazquez,Carlos Singer,Barbara C. Tilley,Peter Valkovič,Christopher G. Goetz,Glenn T. Stebbins +46 more
TL;DR: In this paper, the authors analyzed MDS-UPDRS scores on Parts I through IV and their differences based on HY stage and disease duration in a large cohort of patients with Parkinson's disease.
Journal ArticleDOI
Speech Biomarkers in Rapid Eye Movement Sleep Behavior Disorder and Parkinson Disease.
Jan Rusz,Jan Rusz,Jan Hlavnička,Michal Novotný,Tereza Tykalová,Amélie Pelletier,Jacques Montplaisir,Jean Gagnon,Petr Dusek,Andrea Galbiati,Sara Marelli,Paul C. Timm,Luke N. Teigen,Annette Janzen,Mahboubeh Habibi,Ambra Stefani,Evi Holzknecht,Klaus Seppi,Elisa Evangelista,Anna Laura Rassu,Yves Dauvilliers,Birgit Högl,Wolfgang H. Oertel,Erik K. St. Louis,Luigi Ferini-Strambi,Evžen Růžička,Ronald B. Postuma,Karel Sonka +27 more
TL;DR: The authors used simple speech recording and high-end pattern analysis to provide sensitive and reliable noninvasive biomarkers of prodromal versus manifest α-synucleinopathy in patients with idiopathic rapid eye movement sleep behavior disorder (iRBD) and early stage Parkinson disease (PD).
Journal ArticleDOI
Development and validation of the automated imaging differentiation in parkinsonism (AID-P): a multicentre machine learning study.
Derek B. Archer,Justin T Bricker,Winston T. Chu,Roxana G. Burciu,Johanna L. McCracken,Song Lai,Stephen A. Coombes,Ruogu Fang,Angelos Barmpoutis,Daniel M. Corcos,Ajay S. Kurani,Trina Mitchell,Mieniecia L. Black,Ellen Herschel,Tanya Simuni,Todd B. Parrish,Cynthia L. Comella,Tao Xie,Klaus Seppi,Nicolaas I. Bohnen,Martijn L.T.M. Müller,Roger L. Albin,Florian Krismer,Guangwei Du,Mechelle M. Lewis,Xuemei Huang,Hong Li,Ofer Pasternak,Nikolaus R. McFarland,Michael S. Okun,David E. Vaillancourt +30 more
TL;DR: This study provides an objective, validated, and generalizable imaging approach to distinguish different forms of Parkinsonian syndromes using multi-site dMRI cohorts.
Journal ArticleDOI
Correlation of dopaminergic terminal dysfunction and microstructural abnormalities of the basal ganglia and the olfactory tract in Parkinson's disease.
Christoph Scherfler,Regina Esterhammer,Michael Nocker,Philipp Mahlknecht,Heike Stockner,Boris Warwitz,Sabine Spielberger,Bernadette Pinter,Eveline Donnemiller,Clemens Decristoforo,Irene Virgolini,Michael Schocke,Werner Poewe,Klaus Seppi +13 more
TL;DR: A significant association between increased mean diffusivity signal and decreased 6-[(18)F] fluorolevodopa uptake is reported, indicating that microstructural degradation of the substantia nigra and the olfactory tract parallels progression of putaminal dopaminergic dysfunction in Parkinson's disease.
Journal ArticleDOI
Free water improves detection of changes in the substantia nigra in parkinsonism: A multisite study
Edward Ofori,Florian Krismer,Roxana G. Burciu,Ofer Pasternak,Johanna L. McCracken,Mechelle M. Lewis,Guangwei Du,Nikolaus R. McFarland,Michael S. Okun,Werner Poewe,Christoph Mueller,Elke R. Gizewski,Michael Schocke,Christian Kremser,Hong Li,Xuemei Huang,Klaus Seppi,David E. Vaillancourt +17 more
TL;DR: Evaluated changes in the substantia nigra using single‐ and bi‐tensor models of diffusion magnetic resonance imaging in PD, MSA, and PSP found them to be related to parkinsonism.