T
Tanya Simuni
Researcher at Northwestern University
Publications - 194
Citations - 13877
Tanya Simuni is an academic researcher from Northwestern University. The author has contributed to research in topics: Parkinson's disease & Medicine. The author has an hindex of 40, co-authored 162 publications receiving 9954 citations. Previous affiliations of Tanya Simuni include University of Pennsylvania & Brown University.
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Journal ArticleDOI
Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.
Christopher G. Goetz,Barbara C. Tilley,Stephanie R. Shaftman,Glenn T. Stebbins,Stanley Fahn,Pablo Martinez-Martin,Werner Poewe,Cristina Sampaio,Matthew B. Stern,Richard Dodel,Bruno Dubois,Robert G. Holloway,Joseph Jankovic,Jaime Kulisevsky,Anthony E. Lang,Andrew J. Lees,Sue Leurgans,Peter A. LeWitt,David L. Nyenhuis,C. Warren Olanow,Olivier Rascol,Anette Schrag,Jeanne A. Teresi,Jacobus J. van Hilten,Nancy R. LaPelle,Pinky Agarwal,Saima Athar,Yvette Bordelan,Helen Bronte-Stewart,Richard Camicioli,Kelvin L. Chou,Wendy Cole,Arif Dalvi,Holly Delgado,Alan Diamond,Jeremy P.R. Dick,John E. Duda,Rodger J. Elble,Carol Evans,V. G. H. Evidente,Hubert H. Fernandez,Susan H. Fox,Joseph H. Friedman,Robin D. Fross,David A. Gallagher,Deborah A. Hall,Neal Hermanowicz,Vanessa K. Hinson,Stacy Horn,Howard I. Hurtig,Un Jung Kang,Galit Kleiner-Fisman,Olga Klepitskaya,Katie Kompoliti,Eugene C. Lai,Maureen L. Leehey,Iracema Leroi,Kelly E. Lyons,Terry McClain,Steven W. Metzer,Janis M. Miyasaki,John C. Morgan,Martha Nance,Joanne Nemeth,Rajesh Pahwa,Sotirios A. Parashos,Jay S. Schneider,Kapil D. Sethi,Lisa M. Shulman,Andrew Siderowf,Monty Silverdale,Tanya Simuni,Mark Stacy,Robert Malcolm Stewart,Kelly L. Sullivan,David M. Swope,Pettaruse M. Wadia,Richard Walker,Ruth H. Walker,William J. Weiner,Jill Wiener,Jayne R. Wilkinson,Joanna M. Wojcieszek,Summer C. Wolfrath,Frederick Wooten,Allen Wu,Theresa A. Zesiewicz,Richard M. Zweig +87 more
TL;DR: The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD.
Journal ArticleDOI
The Parkinson Progression Marker Initiative (PPMI)
Kenneth Marek,Danna Jennings,Shirley Lasch,Andrew Siderowf,Caroline M. Tanner,Tanya Simuni,Christopher S. Coffey,Karl Kieburtz,Emily Flagg,Sohini Chowdhury,Werner Poewe,Brit Mollenhauer,Todd Sherer,Mark Frasier,Claire Meunier,Alice Rudolph,Cindy Casaceli,John Seibyl,Susan Mendick,Norbert Schuff,Ying Zhang,Arthur W. Toga,Karen Crawford,Alison Ansbach,Pasquale De Blasio,Michele Piovella,John Q. Trojanowski,Les Shaw,Andrew B. Singleton,Keith A. Hawkins,Jamie L. Eberling,David W. Russell,Laura Leary,Stewart A. Factor,Barbara Sommerfeld,Penelope Hogarth,Emily Pighetti,Karen Williams,David G. Standaert,Stephanie Guthrie,Robert A. Hauser,Holly Delgado,Joseph Jankovic,Christine Hunter,Matthew B. Stern,Baochan Tran,James B. Leverenz,Marne Baca,Sam Frank,Cathi A. Thomas,Irene H. Richard,Cheryl Deeley,Linda Rees,Fabienne Sprenger,Elisabeth Lang,Holly A. Shill,Sanja Obradov,Hubert H. Fernandez,Adrienna Winters,Daniela Berg,Katharina Gauss,Douglas Galasko,Deborah Fontaine,Zoltan Mari,Melissa Gerstenhaber,David J. Brooks,Sophie Malloy,Paolo Barone,Katia Longo,Tom Comery,Bernard Ravina,Igor D. Grachev,Kim Gallagher,Michelle Collins,Katherine Widnell,Suzanne Ostrowizki,Paulo Fontoura,F. Hoffmann La-Roche,Tony W. Ho,Johan Luthman,Marcel P. van der Brug,Alastair D. Reith,Peggy Taylor +82 more
TL;DR: The Parkinson Progression Marker Initiative (PPMI) is a comprehensive observational, international, multi-center study designed to identify PD progression biomarkers both to improve understanding of disease etiology and course and to provide crucial tools to enhance the likelihood of success of PD modifying therapeutic trials.
Journal ArticleDOI
Neuro-QOL: brief measures of health-related quality of life for clinical research in neurology
David Cella,Jin Shei Lai,Cindy J. Nowinski,David Victorson,Amy H. Peterman,Deborah M. Miller,Francois Bethoux,Allen W. Heinemann,S. Rubin,José E Cavazos,Anthony T. Reder,Robert L. Sufit,Tanya Simuni,Gregory L. Holmes,Andrew Siderowf,Valerie Wojna,Rita K. Bode,Natalie McKinney,Tracy Podrabsky,Katy Wortman,Seung W. Choi,Richard Gershon,Nan E. Rothrock,Claudia S. Moy +23 more
TL;DR: These 13 brief measures of self-reported QOL are reliable and show preliminary evidence of concurrent validity inasmuch as they differentiate people based upon number of reported health conditions and whether those reported conditions impede normal function.
Journal ArticleDOI
Technology in Parkinson's disease: Challenges and opportunities.
Alberto J. Espay,Paolo Bonato,Fatta B. Nahab,Walter Maetzler,John Dean,Jochen Klucken,Bjoern M. Eskofier,Aristide Merola,Fay B. Horak,Anthony E. Lang,Ralf Reilmann,Joseph P. Giuffrida,Alice Nieuwboer,Malcolm K. Horne,Max A. Little,Irene Litvan,Tanya Simuni,E. Ray Dorsey,Michelle A. Burack,Ken Kubota,Anita Kamondi,Catarina Godinho,Jean-Francois Daneault,Georgia Mitsi,Lothar Krinke,J.M. Hausdorff,Bastiaan R. Bloem,Spyros Papapetropoulos +27 more
TL;DR: The work carried out by the task force toward identifying challenges and opportunities in the development of technologies with potential for improving the clinical management and the quality of life of individuals with PD is summarized.
Journal ArticleDOI
Association of Cerebrospinal Fluid β-Amyloid 1-42, T-tau, P-tau181, and α-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease
Ju-Hee Kang,Ju-Hee Kang,David J. Irwin,Alice Chen-Plotkin,Andrew Siderowf,Chelsea Caspell,Christopher S. Coffey,Teresa Waligorska,Peggy Taylor,Sarah Pan,Mark Frasier,Kenneth Marek,Karl Kieburtz,Danna Jennings,Tanya Simuni,Caroline M. Tanner,Andrew B. Singleton,Arthur W. Toga,Sohini Chowdhury,Brit Mollenhauer,John Q. Trojanowski,Leslie M. Shaw,Shirley Lasch,Emily Flagg,Werner Poewe,Todd Sherer,Claire Meunier,Alice Rudolph,Cindy Casaceli,John Seibyl,Susan Mendick,Norbert Schuff,Liz Uribe,Jon W. Yankey,Karen Crawford,Alison Scutti,Paola Casalin,Giulia Malferrari,Keith A. Hawkins,David W. Russell,Laura Leary,Stewart A. Factor,Barbara Sommerfeld,Penelope Hogarth,Emily Pighetti,Karen Williams,David Standaert,Stephanie Guthrie,Robert A. Hauser,Joseph Jankovic,Christine Hunter,Matthew B. Stern,Abigail Darin,James B. Leverenz,Marne Baca,Sam Frank,Cathi-Ann Thomas,Irene Richard,Cheryl Deeley,Linda Rees,Fabienne Sprenger,Wolfgang Oertel,Diana Willeke,Holly A. Shill,Hubert H. Fernandez,Jennifer Mule,Daniela Berg,Katharina Gauss,Douglas Galasko,Deborah Fontaine,Zoltan Mari,Arita McCoy,David Brooks,Bina Shah,Paolo Barone,Stuart Isaacson,Angela James,Alberto J. Espay,Kristy J. Espay,Dominic B. Rowe,Madelaine Ranola +80 more
TL;DR: It is found that measures of CSF Aβ1-42, T-t Tau, P-tau181, and α-synuclein have prognostic and diagnostic potential in early-stage PD.