Koji Matsuo

TL;DR: The findings suggest the possibility of aberrant laterality in neural pathways and connectivity patterns related to the pallidum in schizophrenia, and replicate the rank order of effect sizes for subcortical volumetric changes in schizophrenia reported by the ENIGMA consortium.

TL;DR: The results of this morphometry study indicate that small OFC volume relate to high impulsivity and extend the prior finding that the VMPFC is involved in the circuit modulating impulsivity.

TL;DR: In vivo imaging evidence of abnormal frontolimbic circuit function during working memory processing in individuals with MDD is provided, and MDD patients showed significantly greater left dorsolateral cortex activation during the n-back task compared to the healthy controls.

TL;DR: Although there was no local area where brain volume and MD were significantly correlated with disease severity, FA tended to correlate negatively with total days depressed in the right anterior cingulate and the left frontal white matter, suggesting that the frontolimbic neural circuit might play an important role in the neuropathology of patients with major depressive disorder.

TL;DR: The data suggest that aberrant transcriptional regulation caused by the altered expression of HDACs is associated with the pathophysiology of mood disorders.