D
Derrek P. Hibar
Researcher at Genentech
Publications - 144
Citations - 14354
Derrek P. Hibar is an academic researcher from Genentech. The author has contributed to research in topics: Genome-wide association study & Brain size. The author has an hindex of 49, co-authored 142 publications receiving 11110 citations. Previous affiliations of Derrek P. Hibar include Janssen Pharmaceutica & Johnson & Johnson.
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Journal ArticleDOI
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
T.G.M. van Erp,Derrek P. Hibar,Jerod M. Rasmussen,David C. Glahn,Godfrey D. Pearlson,Ole A. Andreassen,Ingrid Agartz,Ingrid Agartz,Lars T. Westlye,Lars T. Westlye,Unn K. Haukvik,Anders M. Dale,Ingrid Melle,Cecilie B. Hartberg,Oliver Gruber,Bernd Kraemer,David Zilles,Gary Donohoe,Gary Donohoe,Sinead Kelly,Sinead Kelly,Colm McDonald,Derek W. Morris,Derek W. Morris,Dara M. Cannon,Aiden Corvin,Marise W. J. Machielsen,Laura Koenders,L. de Haan,Dick J. Veltman,Theodore D. Satterthwaite,Daniel H. Wolf,R.C. Gur,R.E. Gur,Steven G. Potkin,Daniel H. Mathalon,Daniel H. Mathalon,Bryon A. Mueller,Adrian Preda,Fabio Macciardi,Stefan Ehrlich,Stefan Ehrlich,Esther Walton,Johanna Hass,Vince D. Calhoun,HJ Bockholt,Scott R. Sponheim,Jody M. Shoemaker,N.E.M. van Haren,Hilleke E. Hulshoff Pol,Roel A. Ophoff,Roel A. Ophoff,René S. Kahn,Roberto Roiz-Santiañez,Benedicto Crespo-Facorro,Lei Wang,Kathryn I. Alpert,Erik G. Jönsson,Erik G. Jönsson,Rali Dimitrova,Catherine Bois,Heather C. Whalley,Andrew M. McIntosh,Stephen M. Lawrie,Ryota Hashimoto,Paul M. Thompson,Jessica A. Turner +66 more
TL;DR: Worldwide cooperative analyses of brain imaging data support a profile of subcortical abnormalities in schizophrenia, which is consistent with that based on traditional meta-analytic approaches, and validates that collaborative data analyses can readily be used across brain phenotypes and disorders.
Journal ArticleDOI
Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis
Martine Hoogman,Janita Bralten,Derrek P. Hibar,Maarten Mennes,Marcel P. Zwiers,Lizanne S.J. Schweren,Kimm J. E. van Hulzen,Sarah E. Medland,Elena Shumskaya,Neda Jahanshad,Patrick de Zeeuw,Eszter Szekely,Gustavo Sudre,Thomas Wolfers,Alberdingk M.H. Onnink,Janneke Dammers,Jeanette C. Mostert,Yolanda Vives-Gilabert,Gregor Kohls,Eileen Oberwelland,Jochen Seitz,Martin Schulte-Rüther,Sara Ambrosino,Alysa E. Doyle,Alysa E. Doyle,Marie F. Høvik,Margaretha Dramsdahl,Leanne Tamm,Theo G.M. van Erp,Anders M. Dale,Andrew J. Schork,Annette Conzelmann,Annette Conzelmann,Kathrin C. Zierhut,Ramona Baur,Hazel McCarthy,Yuliya N. Yoncheva,Ana Cubillo,Kaylita Chantiluke,Mitul A. Mehta,Yannis Paloyelis,Sarah Hohmann,Sarah Baumeister,Ivanei E. Bramati,Paulo Mattos,Fernanda Tovar-Moll,Pamela K. Douglas,Tobias Banaschewski,Daniel Brandeis,Jonna Kuntsi,Philip Asherson,Katya Rubia,Clare Kelly,Clare Kelly,Adriana Di Martino,Michael P. Milham,Michael P. Milham,Francisco X. Castellanos,Francisco X. Castellanos,Thomas Frodl,Thomas Frodl,Mariam Zentis,Klaus-Peter Lesch,Klaus-Peter Lesch,Andreas Reif,Paul Pauli,Terry L. Jernigan,Jan Haavik,Jan Haavik,Kerstin J. Plessen,Astri J. Lundervold,Kenneth Hugdahl,Kenneth Hugdahl,Larry J. Seidman,Larry J. Seidman,Joseph Biederman,Nanda Rommelse,Dirk J. Heslenfeld,Catharina A. Hartman,Pieter J. Hoekstra,Jaap Oosterlaan,Georg von Polier,Kerstin Konrad,Oscar Vilarroya,Josep Antoni Ramos-Quiroga,Joan Carles Soliva,Sarah Durston,Jan K. Buitelaar,Stephen V. Faraone,Stephen V. Faraone,Philip Shaw,Paul M. Thompson,Barbara Franke +92 more
TL;DR: Lifespan analyses suggest that, in the absence of well powered longitudinal studies, the ENIGMA cross-sectional sample across six decades of ages provides a means to generate hypotheses about lifespan trajectories in brain phenotypes.
Journal ArticleDOI
HHS Public Access
Martine Hoogman,Janita Bralten,Derrek P. Hibar,Maarten Mennes,Marcel P. Zwiers,Lizanne S.J. Schweren,Kimm J. E. van Hulzen,Sarah E. Medland,Elena Shumskaya,Neda Jahanshad,Patrick de Zeeuw,Eszter Szekely,Gustavo Sudre,Thomas Wolfers,Alberdingk M.H. Onnink,Janneke Dammers,Jeanette C. Mostert,Yolanda Vives-Gilabert,Gregor Kohls,Eileen Oberwelland,Jochen Seitz,Martin Schulte-Rüther,Sara Ambrosino,Alysa E. Doyle,Marie F. Høvik,Margaretha Dramsdahl,Leanne Tamm,Theo G.M. van Erp,Anders M. Dale,Andrew J. Schork,Annette Conzelmann,Kathrin C. Zierhut,Ramona Baur,Hazel McCarthy,Yuliya N. Yoncheva,Ana Cubillo,Kaylita Chantiluke,Mitul A. Mehta,Yannis Paloyelis,Sarah Hohmann,Sarah Baumeister,Ivanei E. Bramati,Paulo Mattos,Fernanda Tovar-Moll,Pamela K. Douglas,Tobias Banaschewski,Daniel Brandeis,Jonna Kuntsi,Philip Asherson,Katya Rubia,Clare Kelly,Adriana Di Martino,Michael P. Milham,Francisco X. Castellanos,Thomas Frodl,Mariam Zentis,Klaus-Peter Lesch,Andreas Reif,Paul Pauli,Terry L. Jernigan,Jan Haavik,Kerstin J. Plessen,Astri J. Lundervold,Kenneth Hugdahl,Larry J. Seidman,Joseph Biederman,Nanda Rommelse,Dirk J. Heslenfeld,Catharina A. Hartman,Pieter J. Hoekstra,Jaap Oosterlaan,Georg von Polier,Kerstin Konrad,Oscar Vilarroya,Josep Antoni Ramos-Quiroga,Joan Carles Soliva,Sarah Durston,Jan K. Buitelaar,Stephen V. Faraone,Philip Shaw,Paul M. Thompson,Barbara Franke,Stephen M. Smith,Thomas E. Nichols,Amy Taylor,Hannah J. Jones,Hannah M Sallis,George Davey Smith,Debbie A Lawlor,Neil Davies,Evie Stergiakouli,Marcus R. Munafò,Jack Euesden,Kate Tilling,Stan Zammit,T. Kubota,K. Miyake,N. Hariya,K. Mochizuki,Keri S. Rosch,Deana Crocetti,Kathryn Hirabayashi,Martha B. Denckla,Stewart H. Mostofsky,E. Mark Mahone,Simon Ducharme,Matthew D. Albaugh,Tuong Vi Nguyen,James J. Hudziak,J. M. Mateos-Pérez,Aurelie Labbe,Alan C. Evans,Sherif Karama,William S. Ball,Anna Weber Byars,Mark Schapiro,Wendy Bommer,April Carr,April German,Scott Dunn,Michael J. Rivkin,Deborah Waber,Robert Mulkern,Sridhar Vajapeyam,Abigail Chiverton,Peter Davis,Julie Koo,Jacki Marmor,Christine Mrakotsky,Richard Robertson,Gloria McAnulty,Michael E. Brandt,Jack M. Fletcher,Larry A. Kramer,Grace Yang,Cara McCormack,Kathleen M. Hebert,Hilda Volero,Kelly Botteron,Robert C. McKinstry,William Warren,Tomoyuki Nishino,C. Robert Almli,Richard Todd,John Constantino,Jennifer Levitt,Jeffry R. Jeffrey Alger,Joseph O'Neil,Arthur W. Toga,Robert Asarnow,David Fadale,Laura Heinichen,Cedric Ireland,Dah Jyuu Wang,Edward Moss,Robert A. Zimmerman,Brooke Bintliff,Ruth Bradford,Janice Newman,Rozalia Arnaoutelis,G. Bruce Pike,D. Louis Collins,Gabriel Leonard,Tomáš Paus,Alex Zijdenbos,Samir Das,Vladimir Fonov,Luke Fu,Jonathan Harlap,Ilana Leppert,Denise Milovan,Dario Vins,Thomas Zeffiro,John Van Meter,Nicholas Lange,Michael P. Froimowitz,Cheryl Rainey,Stan Henderson,Jennifer L. Edwards,Diane Dubois,Karla Smith,Tish Singer,Aaron A. Wilber,Carlo Pierpaoli,Peter J. Basser,Lin Ching Chang,Chen Guan Koay,Lindsay Walker,Lisa Freund,Judith Rumsey,Lauren Baskir,Laurence Stanford,Karen Sirocco,Katrina Gwinn-Hardy,Giovanna Spinella,James T. McCracken,Joseph O'Neill,Helen Brinson,Avijit Banik,Deepika Kandilya,Seshadri Ramya,Walter Stünkel,Yap Seng Chong,S. Thameem Dheen,Yuliya S. Nikolova,Ahmad R. Hariri,Wenjun Zhang,Xiuxia Qu,Biyi Chen,Marylynn Snyder,Baiyan Li,Yue Tang,Hanying Chen,Wuqiang Zhu,Ni Yin,Deqiang Li,Xie Li,Ying Liu,J Jillian,Xin-yuan Fu,Michael Rubart,Long-sheng Song,Weinian Shou,Peking Union Medical,Iowa City,Corinde E. Wiers,Brock Medsker,Erick Forno,Hyagriv Simhan,C Juan,Ravi Bansal,Hongtu Zhu,Ronald Whiteman,Georgette A Quackenbush,Laura Martin,Kathleen Durkin,Jason Royal,Bradley S. Peterson,Martha O Wang,Charlotte E Vorwald,Maureen L Dreher,Eric J Mott,Ali Cinar,Hamidreza Mehdizadeh,Sami Somo,David Dean,Eric M Brey,John P Fisher +247 more
Journal ArticleDOI
Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group.
Lianne Schmaal,Derrek P. Hibar,Philipp G. Sämann,Geoffrey B. Hall,Bernhard T. Baune,Neda Jahanshad,Joshua W. Cheung,T.G.M. van Erp,Daniel Bos,M. A. Ikram,Meike W. Vernooij,Wiro J. Niessen,Wiro J. Niessen,Henning Tiemeier,Henning Tiemeier,A. Hofman,Katharina Wittfeld,Hans-Jörgen Grabe,Hans-Jörgen Grabe,Deborah Janowitz,Robin Bülow,M Selonke,Henry Völzke,Dominik Grotegerd,Udo Dannlowski,Udo Dannlowski,Volker Arolt,Nils Opel,Walter Heindel,Harald Kugel,D. Hoehn,Michael Czisch,Baptiste Couvy-Duchesne,Baptiste Couvy-Duchesne,Miguel E. Rentería,Lachlan T. Strike,Margaret J. Wright,Natalie T. Mills,Natalie T. Mills,G.I. de Zubicaray,Katie L. McMahon,Sarah E. Medland,Nicholas G. Martin,Nathan A. Gillespie,Roberto Goya-Maldonado,Oliver Gruber,Bernd Krämer,Sean N. Hatton,Jim Lagopoulos,Ian B. Hickie,Thomas Frodl,Thomas Frodl,Angela Carballedo,Eva-Maria Frey,L. S. van Velzen,B.W.J.H. Penninx,M-J van Tol,N.J. van der Wee,Christopher G. Davey,Ben J. Harrison,Benson Mwangi,Bo Cao,Jair C. Soares,Ilya M. Veer,Henrik Walter,D. Schoepf,Bartosz Zurowski,Carsten Konrad,Elisabeth Schramm,Claus Normann,Knut Schnell,Matthew D. Sacchet,Ian H. Gotlib,Glenda MacQueen,Beata R. Godlewska,Thomas Nickson,Andrew M. McIntosh,Andrew M. McIntosh,Martina Papmeyer,Martina Papmeyer,Heather C. Whalley,Jeremy Hall,Jeremy Hall,J.E. Sussmann,Meng Li,Martin Walter,Martin Walter,Lyubomir I. Aftanas,Ivan Brack,Nikolay A. Bokhan,Nikolay A. Bokhan,Nikolay A. Bokhan,Paul M. Thompson,Dick J. Veltman +93 more
TL;DR: In this article, the authors present the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorder Working Group on cortical structural alterations in MDD.
Journal ArticleDOI
Common genetic variants influence human subcortical brain structures.
Derrek P. Hibar,Jason L. Stein,Jason L. Stein,Miguel E. Rentería,Alejandro Arias-Vasquez,Sylvane Desrivières,Neda Jahanshad,Roberto Toro,Roberto Toro,Katharina Wittfeld,Katharina Wittfeld,Lucija Abramovic,Micael Andersson,Benjamin S. Aribisala,Benjamin S. Aribisala,Nicola J. Armstrong,Nicola J. Armstrong,Manon Bernard,Marc M. Bohlken,Marco P. Boks,Janita Bralten,Andrew A. Brown,M. Mallar Chakravarty,M. Mallar Chakravarty,Qiang Chen,Christopher R.K. Ching,Christopher R.K. Ching,Gabriel Cuellar-Partida,Anouk den Braber,Sudheer Giddaluru,Aaron Goldman,Oliver Grimm,Tulio Guadalupe,Johanna Hass,Girma Woldehawariat,Avram J. Holmes,Avram J. Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil Lee,Phil Lee,Loes M. Olde Loohuis,Michelle Luciano,Christine Macare,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Yuri Milaneschi,Kwangsik Nho,Martina Papmeyer,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Shannon L. Risacher,Roberto Roiz-Santiañez,Emma J. Rose,Alireza Salami,Alireza Salami,Philipp G. Sämann,Lianne Schmaal,Andrew J. Schork,Jean Shin,Lachlan T. Strike,Lachlan T. Strike,Alexander Teumer,Marjolein M.J. van Donkelaar,Kristel R. van Eijk,Raymond K. Walters,Raymond K. Walters,Lars T. Westlye,Christopher D. Whelan,Anderson M. Winkler,Anderson M. Winkler,Marcel P. Zwiers,Saud Alhusaini,Saud Alhusaini,Lavinia Athanasiu,Stefan Ehrlich,Stefan Ehrlich,Marina Hakobjan,Cecilie B. Hartberg,Unn K. Haukvik,Angelien Heister,D. Hoehn,Dalia Kasperaviciute,Dalia Kasperaviciute,David C. Liewald,Lorna M. Lopez,Remco R. R. Makkinje,Mar Matarin,Marlies Naber,D. Reese McKay,Margaret Needham,Allison C. Nugent,Benno Pütz,Natalie A. Royle,Li Shen,Emma Sprooten,Emma Sprooten,Daniah Trabzuni,Daniah Trabzuni,Saskia S. L. van der Marel,Kimm J. E. van Hulzen,Esther Walton,Christiane Wolf,Laura Almasy,Laura Almasy,David Ames,David Ames,Sampath Arepalli,Amelia A. Assareh,Mark E. Bastin,Henry Brodaty,Kazima B. Bulayeva,Melanie A. Carless,Sven Cichon,Sven Cichon,Aiden Corvin,Joanne E. Curran,Michael Czisch,Greig I. de Zubicaray,Allissa Dillman,Ravi Duggirala,Thomas D. Dyer,Thomas D. Dyer,Susanne Erk,Iryna O. Fedko,Luigi Ferrucci,Tatiana Foroud,Peter T. Fox,Peter T. Fox,Masaki Fukunaga,J. Raphael Gibbs,J. Raphael Gibbs,Harald H H Göring,Robert C. Green,Sebastian Guelfi,Narelle K. Hansell,Catharina A. Hartman,Katrin Hegenscheid,Andreas Heinz,Dena G. Hernandez,Dena G. Hernandez,Dirk J. Heslenfeld,Pieter J. Hoekstra,Florian Holsboer,Georg Homuth,Jouke-Jan Hottenga,Masashi Ikeda,Clifford R. Jack,Mark Jenkinson,Robert Johnson,Ryota Kanai,Ryota Kanai,Maria Keil,Jack W. Kent,Peter Kochunov,John B.J. Kwok,John B.J. Kwok,Stephen M. Lawrie,Xinmin Liu,Xinmin Liu,Dan L. Longo,Katie L. McMahon,Eva M. Meisenzahl,Ingrid Melle,Sebastian Mohnke,Grant W. Montgomery,Jeanette C. Mostert,Thomas W. Mühleisen,Mike A. Nalls,Thomas E. Nichols,Thomas E. Nichols,Lars Nilsson,Markus M. Nöthen,Kazutaka Ohi,Rene L. Olvera,Rocío Pérez-Iglesias,G. Bruce Pike,Steven G. Potkin,Ivar Reinvang,Simone Reppermund,Marcella Rietschel,Nina Romanczuk-Seiferth,Glenn D. Rosen,Dan Rujescu,Knut Schnell,Peter R. Schofield,Peter R. Schofield,Colin Smith,Vidar M. Steen,Jessika E. Sussmann,Anbupalam Thalamuthu,Arthur W. Toga,Bryan J. Traynor,Juan C. Troncoso,Jessica A. Turner,Maria C. Valdés Hernández,Dennis van 't Ent,Marcel P. van der Brug,Nic J.A. van der Wee,Marie-José van Tol,Dick J. Veltman,Thomas H. Wassink,Eric Westman,Ronald H. Zielke,Alan B. Zonderman,David G. Ashbrook,Reinmar Hager,Lu Lu,Lu Lu,Francis J. McMahon,Derek W. Morris,Derek W. Morris,Robert W. Williams,Han G. Brunner,Han G. Brunner,Randy L. Buckner,Jan K. Buitelaar,Wiepke Cahn,Vince D. Calhoun,Vince D. Calhoun,Gianpiero L. Cavalleri,Benedicto Crespo-Facorro,Anders M. Dale,Gareth E. Davies,Norman Delanty,Norman Delanty,Chantal Depondt,Srdjan Djurovic,Wayne C. Drevets,Wayne C. Drevets,Thomas Espeseth,Randy L. Gollub,Beng-Choon Ho,Wolfgang Hoffmann,Wolfgang Hoffmann,Norbert Hosten,René S. Kahn,Stephanie Le Hellard,Andreas Meyer-Lindenberg,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Matthias Nauck,Lars Nyberg,Massimo Pandolfo,Brenda W.J.H. Penninx,Joshua L. Roffman,Sanjay M. Sisodiya,Jordan W. Smoller,Jordan W. Smoller,Hans van Bokhoven,Neeltje E.M. van Haren,Henry Völzke,Henrik Walter,Michael W. Weiner,Wei Wen,Tonya White,Ingrid Agartz,Ingrid Agartz,Ole A. Andreassen,John Blangero,John Blangero,Dorret I. Boomsma,Rachel M. Brouwer,Dara M. Cannon,Dara M. Cannon,Mark R. Cookson,Eco J. C. de Geus,Ian J. Deary,Gary Donohoe,Gary Donohoe,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Clyde Francks,Clyde Francks,David C. Glahn,Hans J. Grabe,Oliver Gruber,Oliver Gruber,John Hardy,Ryota Hashimoto,Hilleke E. Hulshoff Pol,Erik G. Jönsson,Erik G. Jönsson,Iwona Kłoszewska,Simon Lovestone,Simon Lovestone,Venkata S. Mattay,Patrizia Mecocci,Colm McDonald,Andrew M. McIntosh,Roel A. Ophoff,Roel A. Ophoff,Tomáš Paus,Zdenka Pausova,Mina Ryten,Mina Ryten,Perminder S. Sachdev,Andrew J. Saykin,Andrew J. Saykin,Andrew Simmons,Andrew B. Singleton,Hilkka Soininen,Joanna M. Wardlaw,Michael E. Weale,Daniel R. Weinberger,Hieab H.H. Adams,Lenore J. Launer,Stephan Seiler,Reinhold Schmidt,Ganesh Chauhan,Claudia L. Satizabal,Claudia L. Satizabal,James T. Becker,Lisa R. Yanek,Sven J. van der Lee,Maritza Ebling,Bruce Fischl,Bruce Fischl,W. T. Longstreth,Douglas N. Greve,Helena Schmidt,Paul A. Nyquist,Louis N. Vinke,Cornelia M. van Duijn,Luting Xue,Bernard Mazoyer,Joshua C. Bis,Vilmundur Gudnason,Sudha Seshadri,Sudha Seshadri,M. Arfan Ikram,Nicholas G. Martin,Margaret J. Wright,Margaret J. Wright,Gunter Schumann,Barbara Franke,Barbara Franke,Paul M. Thompson,Sarah E. Medland +344 more
TL;DR: In this paper, the authors conduct genome-wide association studies of the volumes of seven subcortical regions and the intracranial volume derived from magnetic resonance images of 30,717 individuals from 50 cohorts.