L
Lei Liu
Researcher at Chinese Academy of Sciences
Publications - 358
Citations - 11418
Lei Liu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 44, co-authored 272 publications receiving 8110 citations. Previous affiliations of Lei Liu include University of Science and Technology of China & Northwestern University.
Papers
More filters
Journal ArticleDOI
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2.
Yan Wu,Yan Wu,Feiran Wang,Feiran Wang,Chenguang Shen,Weiyu Peng,Weiyu Peng,Delin Li,Cheng Zhao,Zhaohui Li,Shihua Li,Yuhai Bi,Yang Yang,Yuhuan Gong,Haixia Xiao,Zheng Fan,Shuguang Tan,Guizhen Wu,Wenjie Tan,Xuancheng Lu,Changfa Fan,Qihui Wang,Yingxia Liu,Chen Zhang,Jianxun Qi,George F. Gao,Feng Gao,Lei Liu +27 more
TL;DR: In isolation of four human-origin monoclonal antibodies from a convalescent patient, all of which display neutralization abilities, a therapeutic study in a mouse model validated that these antibodies can reduce virus titers in infected lungs.
Journal ArticleDOI
Heteroepitaxial Growth of Two-Dimensional Hexagonal Boron Nitride Templated by Graphene Edges
Lei Liu,Jewook Park,David Siegel,Kevin F. McCarty,Kendal Clark,Wan Deng,Leonardo Basile,Leonardo Basile,Juan Carlos Idrobo,An-Ping Li,Gong Gu +10 more
TL;DR: By adapting the concept of epitaxy to two-dimensional space, this work shows the growth of a single-atomic-layer, in-plane heterostructure of a prototypical material system—graphene and hexagonal boron nitride (h-BN).
Journal ArticleDOI
A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy
Guo Chen,Zhe Han,Du Feng,Yanfang Chen,Linbo Chen,Hao Wu,Li Huang,Changqian Zhou,Xiangyu Cai,Changying Fu,Liangwei Duan,Xiaohui Wang,Lei Liu,Xinqi Liu,Yuequan Shen,Yushan Zhu,Quan Chen,Quan Chen +17 more
TL;DR: The results reveal a mechanistic signaling pathway linking mitochondria-damaging signals to the dephosphorylation of FUNDC1 by PGAM5, which ultimately induces mitophagy.
Journal ArticleDOI
ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
Wenxian Wu,Weili Tian,Zhe Hu,Guo Chen,Lei Huang,Wen Li,Xingli Zhang,Peng Xue,Changqian Zhou,Lei Liu,Yushan Zhu,Xingliang Zhang,Longxuan Li,Liangqing Zhang,Sen-Fang Sui,Bin Zhao,Du Feng +16 more
TL;DR: It is shown that FUNDC1 regulates ULK1 recruitment to damaged mitochondria, where FUNDC 1 phosphorylation by ULK 1 is crucial for mitophagy.
Journal ArticleDOI
Universal mechanical exfoliation of large-area 2D crystals
Yuan Huang,Yuhao Pan,Rong Yang,Lihong Bao,Lei Meng,Hailan Luo,Yongqing Cai,Guodong Liu,Wenjuan Zhao,Zhang Zhou,Liangmei Wu,Zhi-Li Zhu,Ming Huang,Liwei Liu,Lei Liu,Peng Cheng,Kehui Wu,Shibing Tian,Changzhi Gu,Youguo Shi,Yanfeng Guo,Zhi Gang Cheng,Jiangping Hu,Lin Zhao,Guanhua Yang,Eli Sutter,Peter Sutter,Yeliang Wang,Yeliang Wang,Wei Ji,Xingjiang Zhou,Hong-Jun Gao +31 more
TL;DR: In this article, a contamination-free, one-step and universal Au-assisted mechanical exfoliation method was proposed to isolate 40 types of single-crystalline monolayers, including elemental two-dimensional crystals, metal-dichalcogenides, magnets and superconductors.