Leticia Quintanilla-Martinez

TL;DR: It is demonstrated that stemness and immune evasion are closely intertwined in AML and a strong rationale for targeting therapy-resistant LSCs by PARP1 inhibition, which renders them amenable to control by NK cells in vivo is provided.

TL;DR: It is indicated that these tumors are clinically and biologically similar to the conventional cyclin D1(+) MCL and provides a basis for the proper identification and clinical management of these patients.

TL;DR: It is suggested that in addition to their role in innate immunity against exogenous pathogens, nucleic acid-recognizing Toll-like receptors 3, 7, and 9 contribute to the immune control of activated ERVs and ERV-induced tumors.

TL;DR: It is shown that the mineralocorticoid receptor antagonist spironolactone reduced vascular and soft tissue calcification and increased the life span of kl/kl mice, without significant effects on 1,25(OH)2D3, FGF23, calcium, and phosphate plasma concentrations.

TL;DR: The clinicopathological features of 20 Mexican children with HVLL, an EBV-associated lymphoproliferative disorder of αβ-, γδ-, or NK-cell phenotype with a broad clinical spectrum, usually prolonged clinical course, and risk for progression to systemic disease, are presented.