L
Lijia Dong
Researcher at Peking Union Medical College
Publications - 23
Citations - 1923
Lijia Dong is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Cell cycle & Cell growth. The author has an hindex of 16, co-authored 23 publications receiving 1617 citations.
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Journal ArticleDOI
Identification of genomic alterations in oesophageal squamous cell cancer
Yongmei Song,Lin Li,Yunwei Ou,Zhibo Gao,En-Min Li,Xiangchun Li,Weimin Zhang,Jiaqian Wang,Li-Yan Xu,Yong Zhou,Xiao-Juan Ma,Lingyan Liu,Zitong Zhao,Xuanlin Huang,Jing Fan,Lijia Dong,Gang Chen,Liying Ma,Jie Yang,Chen Longyun,Minghui He,Li Miao,Xuehan Zhuang,Kai Huang,Kunlong Qiu,Guangliang Yin,Guangwu Guo,Qiang Feng,Peishan Chen,Zhi-Yong Wu,Jian-Yi Wu,Ling Ma,Jinyang Zhao,Longhai Luo,Ming Fu,Bainan Xu,Bo Chen,Yingrui Li,Tong Tong,Mingrong Wang,Zhihua Liu,Dongxin Lin,Xiuqing Zhang,Huanming Yang,Jun Wang,Qimin Zhan +45 more
TL;DR: Genomic analyses suggest that ESCC and head and neck squamous cell carcinoma share some common pathogenic mechanisms, and ESCC development is associated with alcohol drinking, and novel biological markers and tumorigenic pathways that would greatly improve therapeutic strategies for ESCC are explored.
Journal ArticleDOI
Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma.
Tong Tong,Yali Zhong,Jianping Kong,Lijia Dong,Yongmei Song,Ming Fu,Zhihua Liu,Ming-Rong Wang,Liping Guo,Shixin Lu,Ming Wu,Qimin Zhan +11 more
TL;DR: The findings presented in this report show that Aurora-A expression is elevated in human esophageal squamous cell carcinoma and is possibly associated with tumor invasion, indicating that overexpression of Aurora- A may contribute to ESCC occurrence and progression.
Journal ArticleDOI
RRLC-MS/MS-based metabonomics combined with in-depth analysis of metabolic correlation network: finding potential biomarkers for breast cancer.
Yanhua Chen,Ruiping Zhang,Yongmei Song,Jiuming He,Jianghao Sun,Jinfa Bai,Zhuoling An,Lijia Dong,Qimin Zhan,Zeper Abliz +9 more
TL;DR: These studies demonstrate the advantages of integrating metabolic correlation networks with metabonomics for finding significant potential biomarkers and can even provide biochemical insights into changes in breast cancer.
Journal ArticleDOI
Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/β-catenin pathway
Runsheng Chen,Yongmei Song,Zhongmei Zhou,Tong Tong,Youzan Li,Ming Fu,Xiaoli Guo,Lijia Dong,Xin He,Hong Qiao,Qimin Zhan,Wei Li +11 more
TL;DR: The role of xCT in tumor metastasis is established and a potential target for cancer therapy is implicate and revealed that the upregulation of caveolin-1 and inhibition of tumor cell invasion were mediated by reactive oxygen species-induced p38 MAPK activation.
Journal ArticleDOI
Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers
Jing Xu,Yanhua Chen,Ruiping Zhang,Yongmei Song,Jianzhong Cao,N. Bi,Jingbo Wang,Jiuming He,Jinfa Bai,Lijia Dong,Luhua Wang,Qimin Zhan,Zeper Abliz +12 more
TL;DR: The results suggest that these biomarkers may be useful in diagnosis, as well as in monitoring therapeutic responses and predicting outcomes of the ESCC.