G
Guangliang Yin
Researcher at Beijing Genomics Institute
Publications - 10
Citations - 1435
Guangliang Yin is an academic researcher from Beijing Genomics Institute. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 9, co-authored 10 publications receiving 1211 citations. Previous affiliations of Guangliang Yin include The Breast Cancer Research Foundation & Beijing Institute of Genomics.
Papers
More filters
Journal ArticleDOI
Identification of genomic alterations in oesophageal squamous cell cancer
Yongmei Song,Lin Li,Yunwei Ou,Zhibo Gao,En-Min Li,Xiangchun Li,Weimin Zhang,Jiaqian Wang,Li-Yan Xu,Yong Zhou,Xiao-Juan Ma,Lingyan Liu,Zitong Zhao,Xuanlin Huang,Jing Fan,Lijia Dong,Gang Chen,Liying Ma,Jie Yang,Chen Longyun,Minghui He,Li Miao,Xuehan Zhuang,Kai Huang,Kunlong Qiu,Guangliang Yin,Guangwu Guo,Qiang Feng,Peishan Chen,Zhi-Yong Wu,Jian-Yi Wu,Ling Ma,Jinyang Zhao,Longhai Luo,Ming Fu,Bainan Xu,Bo Chen,Yingrui Li,Tong Tong,Mingrong Wang,Zhihua Liu,Dongxin Lin,Xiuqing Zhang,Huanming Yang,Jun Wang,Qimin Zhan +45 more
TL;DR: Genomic analyses suggest that ESCC and head and neck squamous cell carcinoma share some common pathogenic mechanisms, and ESCC development is associated with alcohol drinking, and novel biological markers and tumorigenic pathways that would greatly improve therapeutic strategies for ESCC are explored.
Journal ArticleDOI
An atlas of DNA methylomes in porcine adipose and muscle tissues
Mingzhou Li,Honglong Wu,Zonggang Luo,Zonggang Luo,Yudong Xia,Jiuqiang Guan,Tao Wang,Yiren Gu,Lei Chen,Kai Zhang,Jideng Ma,Yingkai Liu,Zhijun Zhong,Jing Nie,Shuling Zhou,Zhiping Mu,Xiaoyan Wang,Jingjing Qu,Long Jing,Huiyu Wang,Shujia Huang,Na Yi,Zhe Wang,Dongxing Xi,Juan Wang,Guangliang Yin,Li Wang,Ning Li,Zhi Jiang,Qiulei Lang,Huasheng Xiao,Anan Jiang,Li Zhu,Yanzhi Jiang,Guoqing Tang,Miaomiao Mai,Surong Shuai,Kui Li,Jinyong Wang,Xiuqing Zhang,Yingrui Li,Haosi Chen,Xiaolian Gao,Graham Plastow,Stephen Beck,Huanming Yang,Jian Wang,Jun Wang,Xuewei Li,Ruiqiang Li +49 more
TL;DR: This comprehensive map provides a solid basis for exploring the epigenetic mechanisms of adipose deposition and muscle growth in pig as a model and identifies the differentially methylated regions in promoters.
Journal ArticleDOI
Genome-Wide Mapping of DNA Methylation in Chicken
Qinghe Li,Ning Li,Ning Li,Xiaoxiang Hu,Jinxiu Li,Zhuo Du,Li Chen,Guangliang Yin,Jinjie Duan,Haichao Zhang,Yaofeng Zhao,Jun Wang +11 more
TL;DR: The genome-wide DNA methylation map of bird is shown, using the chicken as a model organism and an immunocapturing approach followed by high-throughput sequencing to contribute to the understanding of epigenetics in birds.
Journal ArticleDOI
Genomic heterogeneity of multiple synchronous lung cancer
Yu Liu,Jianjun Zhang,Lin Li,Guangliang Yin,Jianhua Zhang,Shan Zheng,Hannah Cheung,Ning Wu,Ning Lu,Xizeng Mao,L. Yang,Jiexin Zhang,Li Zhang,Sahil Seth,Huang Chen,Xingzhi Song,Kan Liu,Yong-qiang Xie,Lina Zhou,Chuanduo Zhao,Naijun Han,W Q Chen,Susu Zhang,Chen Longyun,Wenjun Cai,Miaozhong Shen,Ningzhi Xu,Shujun Cheng,Huanming Yang,J. Jack Lee,Arlene M. Correa,Junya Fujimoto,Carmen Behrens,Chi Wan Chow,William N. William,John V. Heymach,Waun Ki Hong,Stephen G. Swisher,Ignacio I. Wistuba,Jun Wang,Jun Wang,Dongmei Lin,Xiangyang Liu,P. Andrew Futreal,Yanning Gao +44 more
TL;DR: Analysis of genomic profiles of 15 lung adenocarcinomas and one regional lymph node metastasis from 6 patients with MSLC suggests different lung cancers in the same individual may have distinct genomic profiles and can be driven by distinct molecular events.
Journal ArticleDOI
Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties
Xue Lin,Xue Lin,Jian Li,Guangliang Yin,Qian Zhao,Daniel Elias,Daniel Elias,Anne E. Lykkesfeldt,Jan Stenvang,Jan Stenvang,Nils Brünner,Nils Brünner,Jun Wang,Huanming Yang,Lars Bolund,Lars Bolund,Henrik J. Ditzel,Henrik J. Ditzel,Henrik J. Ditzel +18 more
TL;DR: The data highlight the likelihood that resistant cells emerge from cancer-initiating cells/cancer stem-like cells and imply that these cells may gain further advantage in growth via epigenetic mechanisms and suggest novel strategies to overcome tamoxifen resistance.