L
Luis M. Montuenga
Researcher at University of Navarra
Publications - 245
Citations - 10844
Luis M. Montuenga is an academic researcher from University of Navarra. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 48, co-authored 221 publications receiving 9205 citations. Previous affiliations of Luis M. Montuenga include Chartered Institute of Management Accountants & Carlos III Health Institute.
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Journal ArticleDOI
A microRNA DNA methylation signature for human cancer metastasis
Amaia Lujambio,George A. Calin,Alberto Villanueva,Santiago Ropero,Montserrat Sanchez-Cespedes,David Blanco,Luis M. Montuenga,Simona Rossi,Milena S. Nicoloso,William J. Faller,William M. Gallagher,Suzanne A. Eccles,Carlo M. Croce,Manel Esteller +13 more
TL;DR: Findings indicate that DNA methylation-associated silencing of tumor suppressor miRNAs contributes to the development of human cancer metastasis.
Journal ArticleDOI
Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer
Scott N. Gettinger,Jungmin Choi,Katherine Hastings,Anna Truini,Ila Datar,Ryan T. Sowell,Anna Wurtz,Weilai Dong,Guoping Cai,Mary Ann Melnick,Victor Y. Du,Joseph Schlessinger,Sarah B. Goldberg,Anne C. Chiang,Miguel F. Sanmamed,Ignacio Melero,Jackeline Agorreta,Luis M. Montuenga,Richard P. Lifton,Soldano Ferrone,Paula B. Kavathas,David L. Rimm,Susan M. Kaech,Kurt A. Schalper,Roy S. Herbst,Katerina Politi +25 more
TL;DR: CRISPR-mediated knockout of B2m in an immunocompetent lung cancer mouse model conferred resistance to PD-1 blockade in vivo, proving its role in resistance to ICIs.
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Assessing the relationship between lung cancer risk and emphysema detected on low-dose CT of the chest.
Juan P. de Torres,Gorka Bastarrika,Juan P. Wisnivesky,Ana B. Alcaide,Arantza Campo,Luis M. Seijo,Jesus Pueyo,Alberto Villanueva,Maria D. Lozano,Usua Montes,Luis M. Montuenga,Javier J. Zulueta +11 more
TL;DR: Results suggest that the presence of emphysema on low-radiation-dose CT of the chest is an independent risk factor for lung cancer.
Journal ArticleDOI
Alternative splicing: an emerging topic in molecular and clinical oncology
TL;DR: The current knowledge on the mechanisms governing abnormal alternativesplicing in cancer and the biological consequences associated with the alteration of splicing in some relevant cancer-related genes are summarized.
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Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges
Luis M. Seijo,Nir Peled,Daniel Ajona,Mattia Boeri,John K. Field,Gabriella Sozzi,Ruben Pio,Javier J. Zulueta,Avrum Spira,Pierre P. Massion,Peter J. Mazzone,Luis M. Montuenga +11 more
TL;DR: The present review is an update of the research and development efforts regarding the use of molecular biomarkers in the lung cancer screening setting and proposes some principles to optimize lung cancer biomarker discovery projects.