Luis M. Ruilope

TL;DR: Captopril supports the concept that captopril may have salutary effects on the glomerulus, independently of its effect on systemic blood pressure.

TL;DR: Data are reported indicating for the first time that a decrease in urinary albumin excretion rate is accompanied by a significant decrease in cardiovascular events, providing the first evidence showing that regression of an intermediate end-point, microalbuminuria, ensures a better cardiovascular prognosis.

TL;DR: The combination of the standard therapy with an ACEi or an ARB with a mineralocorticoid receptor blocker is a valid option, but has the inconvenience of frequent hyperkalemia in patients with CKD.

TL;DR: Data suggest that serelaxin acts via multiple pathways to improve haemodynamics at the vascular, cardiac, and renal level and provide effective congestion relief, and may protect the heart, kidneys, and liver from damage by inhibiting inflammation, oxidative stress, cell death, and tissue fibrosis, and stimulating angiogenesis.

TL;DR: Valsartan is effective in the treatment of posttransplant hypertension and is well tolerated, and a statistically but not clinically significant reduction was observed in the mean hemoglobin concentration.